Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was …

… b, The negative-feedback control hypothesis for vascular energy supply, in which a fall in
energy level induces an increased cerebral blood flow (CBF). c, The feedforward regulation …

Neuronal communication underlies all brain activity and the genesis of complex behavior.
Emerging research has revealed an unexpected role for immune molecules in the …

… 0 ), where F 1 and F 0 are fluorescence in the astrocyte endfoot at any given time point
and at the beginning of the experiment respectively, and B 1 and B 0 are the background …

Calcium signalling in astrocytes couples changes in neural activity to alterations in cerebral
blood flow by eliciting vasoconstriction or vasodilation of arterioles. However, the …

Neuronal excitotoxicity during stroke is caused by activation of unidentified large-conductance
channels, leading to swelling and calcium dysregulation. We show that ischemic-like …

… In our study (Mulligan and MacVicar, 2004), astrocytes were identified in transgenic mice
that expressed EGFP driven by the GFAP promoter. The astrocytes were loaded with the–AM …

… The control average image for this series is shown in A, and the control subtraction is shown
in B. The intensities of the subtracted images are illustrated as 3-D surface plots where the z-…

Pannexin-1 (Px1) is expressed at postsynaptic sites in pyramidal neurons, suggesting that
these hemichannels contribute to dendritic signals associated with synaptic function. We …

… ReAsH fluorescence (A) Low magnification EM of the same cells (B and C). Higher power
EM of area denoted by an arrow in (B), showed staining at appositional areas between cells, …