Background This is an update of a Cochrane review first published in 2001. At that stage there
was insufficient evidence to recommend statins for the prevention of Alzheimer's disease (…

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of
cognitive impairment and dementia - McGuinness, B - 2009 | Cochrane Library … Thus …

Background The use of statin therapy in established Alzheimer's disease (AD) or vascular
dementia (VaD) is a relatively unexplored area. In AD, β‐amyloid protein (Aβ) is deposited in …

Background Trials of endovascular therapy for ischemic stroke have produced variable
results. We conducted this study to test whether more advanced imaging selection, recently …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease (AD)
involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 (3,941 …

We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

We identified rare coding variants associated with Alzheimer's disease in a three-stage case–control
study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole-…

Background Late Onset Alzheimer's disease (LOAD) is the leading cause of dementia.
Recent large genome-wide association studies (GWAS) identified the first strongly supported …

LONG a student of Wittgenstein's Tractatus and, with Mr David Pears (now Professor), a
translator of it, I came to an interest in Wittgenstein's life through the discovery of various papers …