… Pluripotent stem cells exhibit a specific state of BCL‐2 (B cell lymphoma‐2) family proteins,
… between mitochondrial metabolism and epigenetics in stem cells is shown in Fig 3A and B. …

… Target-Based and Phenotype-Based Drug Discovery … to screen for compounds able to
rescue the expression of I-κ-B kinase complex-associated protein [67]. Another HT option used for …

… (B): BJ fibroblasts were transduced with the four factor cocktail (4F) alone or in
combination with daily treatment with 100 μM EDHB (4F EDHB). All cells were plated under …

… B Bioenergetic assessment B Transmission electron microscopy (TEM) B MMP quantification
in permeabilized cells B … in intact cells B High-content screening (HCS) B Mitochondrial …

Leigh syndrome (LS) is a severe manifestation of mitochondrial disease in children and is
currently incurable. The lack of effective models hampers our understanding of the …

… in WNT signalling of males and females (B); Hierachical clustering showing a similar … (B)
The KEGG-pathway shows genes which are negative regulated with age in green colour…

… Interestingly, the preference for a type B J-protein is not based on the substrate recognition
as we could detect binding of the HttExon1Q 48 fibrils for DNJ-13 (type B) as well as for both …

… (A and B) PC-9 cells were infected with different shRNA constructs targeting EGFR and …
(B) The bar graph shows the mean (+SEM) percentage of EGFR-negative cells from three …

The metabolic switch associated with the reprogramming of somatic cells to pluripotency
has received increasing attention in recent years. However, the impact of mitochondrial and …

… (b) Morphology of 32D cells in the presence of 10 μ M CGP57380. (c, d) Differences in
differentiation status of 32D cells were confirmed by flow cytometry analysis of CD11b surface …