User profiles for B. Sie

Brandon Sie

Harvard Medical School
Verified email at g.harvard.edu
Cited by 915

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

…, RT Timms, IH Lee, Y Leng, ML Robinson, BM Sie… - Science, 2020 - science.org
INTRODUCTION A systematic characterization of the humoral response to severe acute
respiratory system coronavirus 2 (SARS-CoV-2) epitopes has yet to be performed. This analysis …

PhIP-Seq characterization of serum antibodies using oligonucleotide-encoded peptidomes

D Mohan, DL Wansley, BM Sie, MS Noon, AN Baer… - Nature protocols, 2018 - nature.com
b, ELISA is used to quantify each sample’s IgG content for normalizing the amount of antibody
input into each phage-binding reaction. Antibodies and their bound phage are captured …

Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome

…, M Deijs, MH Broeks, C Cristella, B Sie… - Brain …, 2023 - academic.oup.com
… However, using metabolomics, lipidomics and targeted quantification of all vitamin B 6
vitamers on plasma and CSF, we found no evidence of association. Similarly, certain immune or …

Atherosclerotic popliteal aneurysm

I Dawson, RB Sie, JH Van Bockel - Journal of British Surgery, 1997 - academic.oup.com
Background A popliteal artery aneurysm (PAA) has been described as a ‘sinister harbinger
of sudden catastrophe’. This review seeks to provide data regarding the epidemiological …

[PDF][PDF] Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping

Z Zhang, B Sie, A Chang, Y Leng, C Nardone… - Molecular cell, 2023 - cell.com
… motif showed that it matches a canonical b-TrCP degron motif21,22 of which there are two
paralogs, b-TrCP1 and b-TrCP2. Although the canonical b-TrCP degron motifs require one or …

[HTML][HTML] LINE-1 ORF2p expression is nearly imperceptible in human cancers

…, JP Steranka, M Gorbounov, WR Yang, B Sie… - Mobile dna, 2020 - Springer
… 4b exhibits results obtained with Tumor A using a modified … [10]) to tumors A and B. Although
IP from these materials yields … IHC staining results for tumors B and C – corroborating the …

[HTML][HTML] Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes

DR Monaco, BM Sie, TR Nirschl, AC Knight… - Nature …, 2021 - nature.com
Allergic reactions occur when IgE molecules become crosslinked by antigens such as food
proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize …

[HTML][HTML] Relationship between seminal plasma zinc concentration and spermatozoa–zona pellucida binding and the ZP-induced acrosome reaction in subfertile men

DY Liu, BS Sie, ML Liu, F Agresta… - Asian journal of …, 2009 - ncbi.nlm.nih.gov
The aim of this study was to determine the relationship between seminal zinc concentration
and spermatozoa–zona pellucida (ZP) binding and the ZP-induced acrosome reaction (…

Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1γ autoantibodies

Y Hosono, B Sie, I Pinal-Fernandez, K Pak… - Annals of the …, 2023 - ard.bmj.com
Objectives In dermatomyositis (DM), autoantibodies are associated with unique clinical
phenotypes. For example, anti-TIF1γ autoantibodies are associated with an increased risk of …

[PDF][PDF] Comprehensive profiling of HIV antibody evolution

…, K Kammers, A Chen, MV Sivay, S Kottapalli, BM Sie… - Cell reports, 2019 - cell.com
… (C) The blue line shows antibody binding data (normalized read counts) for the parent
peptide included in the analysis in (B) (parent peptide B) and selected variant peptides. Black …