… and the intracellular accumulation of the major proinflammatory cytokines interleukin (IL)-1β
and IL-18 via the master inflammation/immune transcription factor nuclear factor kappa B (NF…

… and megakaryocytes (and possibly also few B lymphocytes and NK cells) through a second
… development and the persistence of some immune cells (ie B-cells) into adulthood (29–33). …

… b, detection of NFAT autoregulation in hearts with calcineurin activation. The data demonstrate
that upon calcineurin/NFAT activation, nfatc1.1, nfatc3.1, and nfatc3.2 splice transcripts …

The E2F family of transcription factors plays an important role in controlling cell‐cycle
progression. While this is their best‐known function, we report here novel functions for the newest …

The adult blood system is established by hematopoietic stem cells (HSCs), which arise during
development from an endothelial-to-hematopoietic transition of cells comprising the floor …

… b Flow of blood was reduced by administering 3x MS222 at indicated time point. c Percentage
of venous ISVs in embryos with reduced blood flow. d Viscosity of blood was reduced by …

… (B′) Enlarged view of the blue node shown in the box in panel B. (CD) Ten first biological
processes in GO terms (C) and most relevant KEGG pathways (D) enriched in the ligand-…

… (A,B) Quantitative PCR was performed to determine vegfaa expression levels in ptena−/−ptenb−/−
mutants compared with wild type at 4 dpf (A) and at 1, 2 and 3 dpf (B). Rescue …

… (A,B,C) qPCR was performed to determine the whole-organism expression of tnfa from 4
hpf to 7 dpf (A), and il1b and il10 from 1 dpf to 7 dpf (B,C), in wild-type or mecp2-null zebrafish. …

… Here, we report that in response to factors that promote cell motility, the Rap guanine
exchange factor RAPGEF2 is rapidly phosphorylated by I-kappa-Bkinase-b and casein kinase-1a …