Drugs that kill tuberculosis more quickly could shorten chemotherapy significantly. In
Escherichia coli, a common mechanism of cell death by bactericidal antibiotics involves the …

… gradient elution by buffer A (50 mM ammonium acetate) and buffer B (MeOH; 97% A to 93%
A in 14 min and 97% B wash from 15 to 22 min). Fluorescence detection was at 370/450 nm. …

… It has also been suggested that σ B may have a role in … , one independent of σ B and the
other possibly σ B dependent. The … As these strains have only weak residual σ B activity, the …

… The gradient began at 40% B and was ramped to 43% B at 2 min, 50% B at 2.1 min, 54%
B at 12 min, 70% B at 12.1 min, 99% B at 18 min, and then back to 40% B at 18.1 min until the …

… (B) M1P accumulation from endogenous trehalose in transposon-… Data in B to D are
representative of at least two independent … (B) Growth kinetics of Mtb trehalose transporter mutants …

… (B and C) Ferrous and ferric ion concentrations were measured in the cell pellets (B) and
supernatants (C) of Mtb mc 2 6230 cultures treated with INH (7.3 μM), cysteine (4.0 mM), or INH/…

New chemotherapeutics are urgently required to control the tuberculosis pandemic. We
describe a new pathway from trehalose to α-glucan in Mycobacterium tuberculosis comprising …

… tuberculosis pellicle using osmium tetroxide vapor (A) or potassium ferrocyanide (B)
processing shows an organized bacterial community. Scale bars represent 10 µm in ×1,000 and 5 …

Many of the virulence factors that have been characterized for group A streptococci (GAS)
are not expressed in all clinical isolates. One putative virulence factor that is present among …

… (B) Up-regulation of genes associated with antioxidant defense, Fe-S cluster biosynthesis,
and DNA repair. (C) Enhanced expression of anaplerotic genes (containing Fe-S) involved in …