… Deletion of the TMR in the HHV-6 genome resulted in a virus that replicates comparable to
parental and revertant viruses (Wallaschek and Kaufer, unpublished data), indicating that the …

Maintenance and manipulation of large DNA and RNA virus genomes had presented an
obstacle for virological research. BAC vectors provided a solution to both problems as they can …

Marek’s disease virus (MDV) infects chickens and causes one of the most frequent cancers
in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a …

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK 1 . Here we report …

Some herpesviruses, particularly lymphotropic viruses such as Marek’s disease virus (MDV)
and human herpesvirus 6 (HHV-6), integrate their DNA into host chromosomes. MDV and …

Herpes simplex encephalitis is a life-threatening disease of the central nervous system
caused by herpes simplex viruses (HSVs). Following standard of care with antiviral acyclovir …

… cell lines (BB Kaufer, BK Tischer, and N. Osterrieder, unpublished observations). Another
explanation might be that ORF9 expression is controlled by the strong HCMV-IE promoter. …

Aims Human herpesvirus 6 ( HHV ‐6) A and B are two betaherpesviruses that are associated
with many conditions including roseola, drug‐induced hypersensitivity syndrome, limbic …

Here we report that negatively charged polysulfates can bind to the spike protein of SARS‐CoV‐2
via electrostatic interactions. Using a plaque reduction assay, we compare inhibition of …

Marek's disease virus (MDV) is a cell-associated and highly oncogenic alphaherpesvirus
that infects chickens. During lytic and latent MDV infection, a CXC chemokine termed viral …