Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes.
Current approaches for transcript reconstruction from such data often rely on aligning …

Motivation: Chimeric DNA sequences often form during polymerase chain reaction
amplification, especially when sequencing single regions (eg 16S rRNA or fungal Internal …

De novo assembly of RNA-seq data enables researchers to study transcriptomes without
the need for a genome sequence; this approach can be usefully applied, for instance, in …

Bacterial diversity among environmental samples is commonly assessed with PCR-amplified
16S rRNA gene (16S) sequences. Perceived diversity, however, can be influenced by …

EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation
tool that reports eukaryotic gene structures as a weighted consensus of all available …

Large panels of comprehensively characterized human cancer models, including the Cancer
Cell Line Encyclopedia (CCLE), have provided a rigorous framework with which to study …

Massively-parallel cDNA sequencing has opened the way to deep and efficient probing of
transcriptomes. Current approaches for transcript reconstruction from such data often rely on …

… These categories are listed in order of correspondence to the illustrations in figure 2 of Haas
… These categories are listed in order of correspondence to the illustrations in figure 2 of Haas …

Phytophthora infestans is the most destructive pathogen of potato and a model organism for
the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms …

Schistosoma mansoni is responsible for the neglected tropical disease schistosomiasis that
affects 210 million people in 76 countries. Here we present analysis of the 363 megabase …