[HTML][HTML] High-throughput organ-on-chip platform with integrated programmable fluid flow and real-time sensing for complex tissue models in drug development …

…, JR Coppeta, EM Vedula, EE Marr, BP Cain… - Lab on a Chip, 2021 - pubs.rsc.org
Drug development suffers from a lack of predictive and human-relevant in vitro models.
Organ-on-chip (OOC) technology provides advanced culture capabilities to generate …

[HTML][HTML] A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions

…, TJ Mulhern, R Strelnikov, H Azizgolshani, BP Cain… - Scientific reports, 2021 - nature.com
… We are also very thankful to Rachel Roth Flach and Michael Cain of Pfizer for their
contributions to scientific discussions. We acknowledge financial support from Pfizer for this work. …

[HTML][HTML] High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro

AL Gard, RJ Luu, CR Miller, R Maloney, BP Cain… - Scientific reports, 2021 - nature.com
Influenza and other respiratory viruses present a significant threat to public health, national
security, and the world economy, and can lead to the emergence of global pandemics such …

[HTML][HTML] Fibroblast activation in response to TGFβ1 is modulated by co-culture with endothelial cells in a vascular organ-on-chip platform

…, MT Rogers, ES Kim, JR Coppeta, BP Cain… - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Background: Tissue fibrosis is a major healthcare burden that affects various organs in the
body for which no effective treatments exist. An underlying, emerging theme across organs …

[HTML][HTML] Proteomic profiling of fallopian tube-derived extracellular vesicles using a microfluidic tissue-on-chip system

…, LE Bantis, A Mitra, RV Puri, CV Trinidad, BP Cain… - Bioengineering, 2023 - mdpi.com
The human fallopian tube epithelium (hFTE) is the site of fertilization, early embryo development,
and the origin of most high-grade serous ovarian cancers (HGSOCs). Little is known …

Versican secreted by the ovary links ovulation and migration in fallopian tube derived serous cancer

A Russo, Z Yang, GM Heyrman, BP Cain, AL Carrero… - Cancer letters, 2022 - Elsevier
High grade serous ovarian cancers (HGSOC) predominantly arise in the fallopian tube
epithelium (FTE) and colonize the ovary first, before further metastasis to the peritoneum. Ovarian …

[HTML][HTML] Increased Local Testosterone Levels Alter Human Fallopian Tube mRNA Profile and Signaling

A Russo, BP Cain, T Jackson-Bey, A Lopez Carrero… - Cancers, 2023 - mdpi.com
Simple Summary Increased testosterone has been associated with increased risk of ovarian
cancer. High Grade Serous Ovarian Carcinoma (HGSOC) mostly originates from the …

Correction: A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditions

…, H Azizgolshani, BC Isenberg, PM Keegan, BP Cain… - Lab on a Chip, 2020 - pubs.rsc.org
Correction for 'A high-throughput microfluidic microphysiological system (PREDICT-96) to
recapitulate hepatocyte function in dynamic, re-circulating flow conditions' by Kelly Tan et al …

A hot water decontamination system for beef sides

VH Powell, BP Cain - CSIRO Food Research Quarterly (Australia), 1987 - agris.fao.org
A prototype microbiological decontamination cabinet for sheep was adapted for use for a beef
slaughter line. The system produced and average temperature of 75 deg C at the surface …

Military medical malpractice and the Feres doctrine

BP Cain - Ga. L. Rev., 1985 - HeinOnline
1 The facts of this case were discussed in Military Medical Malpractice: Hearings on HR
1161 Before the Subcomm. on Admin. Law and Gov't Relations of the House Comm. on the …