Cognitive deficits are very common in Parkinson's disease particularly for ‘executive functions’
associated with frontal cortico-striatal networks. Previous work has identified deficits in …

Although progressive supranuclear palsy is defined by its akinetic rigidity, vertical supranuclear
gaze palsy and falls, cognitive impairments are an important determinant of patients’ and …

Abnormalities of tau protein are central to the pathogenesis of progressive supranuclear
palsy, whereas haplotype variation of the tau gene MAPT influences the risk of Parkinson …

Progressive supranuclear palsy (PSP) is an atypical parkinsonian syndrome characterised
by akinesis, rigidity, falls, supranuclear gaze palsy and cognitive, particularly executive, …

Brain regions related to saccadic control are affected by Parkinson's disease (PD) pathology
and a relationship between abnormal saccades and cognitive features of PD has been …

There is a pressing need to understand the factors that predict prognosis in progressive
supranuclear palsy (PSP) and corticobasal syndrome (CBS), with high heterogeneity over the …

The disruption of large-scale brain networks is increasingly recognised as a consequence of
neurodegenerative dementias. We assessed adults with behavioural variant frontotemporal …

Progressive supranuclear palsy causes diverse clinical presentations, including classical
Richardson’s syndrome and several variant phenotypes. Clinical trials of disease-modifying …

Objective We studied the annual change in measures of motor, oculomotor and cognitive
function in progressive supranuclear palsy. This had twin objectives, to assess the potential for …

Background Studies on early‐onset presentations of progressive supranuclear palsy (PSP)
have been limited to those where a rare monogenic cause has been identified. Here, we …