Microplastics are ubiquitous environmental pollutants that are a growing concern to many
ecosystems, as well as human health. Many of the effects of microplastics on mammalian cells …

Seven norsesterterpene peroxides: epimuqubilin A (1), muqubilone B (2), unnamed cyclic
peroxide ester (3), epimuqubilin B (4), sigmosceptrellin A methyl ester (5), sigmosceptrellin A (…

Objective— Notch signaling has a critical role in vascular development and morphogenesis.
Activation of Notch in endothelial cells led to a senescence-like phenotype with loss of …

Objective— Bone morphogenetic protein-9 (BMP9)/activin-like kinase-1 and delta-like 4 (DLL4)/Notch
promote endothelial quiescence, and we aim to understand mechanistic …

Patients with severe mental illness are more susceptible to infections for a variety of reasons,
some associated with the underlying disease and some due to environmental factors …

Notch signaling plays many important roles in homeostasis and remodeling in the vessel
wall, and serves a critical role in the communication between endothelial cells and smooth …

Patients with severe mental illness have increased mortality, often linked to cardio-metabolic
disease. Non-alcoholic fatty liver disease (NAFLD) incidence is higher in patients with …

Rationale: Deregulated vascular smooth muscle cell (VSMC) proliferation contributes to
multiple vascular pathologies, and Notch signaling regulates VSMC phenotype. Objective: …

The cancer chemopreventive and cytotoxic properties of 50 extracts derived from Twilight
Zone (50–150 m) sponges, gorgonians and associated bacteria, together with 15 extracts from …

Adipose tissue development is dependent on multiple signaling mechanisms and cell-cell
interactions that regulate adipogenesis, angiogenesis and extracellular remodeling. The …