The first lineage choice in human embryo development separates trophectoderm from the
inner cell mass. Naïve human embryonic stem cells are derived from the inner cell mass and …

To understand the epigenomic foundation of naive pluripotency, we implement a quantitative
multiplexed chromatin immunoprecipitation sequencing (ChIP-seq) method comparing …

Mouse embryonic stem cells (mESCs) can adopt naïve, ground, and paused pluripotent states
that give rise to unique transcriptomes. Here, we use transient transcriptome sequencing (…

Transposable elements are efficient DNA carriers and thus important tools for transgenesis
and insertional mutagenesis. However, their poor target sequence specificity constitutes an …

Many strains of Trichoderma fungi have beneficial effects on plant growth and pathogen
control, but little is known about the importance of plant genotype, nor the underlying …

10.7554/eLife.19706.001 Bacterial Xer site-specific recombinases play an essential genome
maintenance role by unlinking chromosome multimers, but their mechanism of action has …

Unique transcriptomes define naïve, primed and paused pluripotent states in mouse embryonic
stem cells. Here we perform transient transcriptome sequencing (TT-seq) to de novo …

Living systems, from entire organisms down to the single cells constituting them aredynamic
entities that continuously adapt and respond to their local environment. Cellsachieve this …

Objective To explore changes in the phenotypic features of Sjögren's syndrome ( SS ), and in
SS status among participants in the Sjögren's International Collaborative Clinical Alliance ( …

A novel method for simultaneous bioflocculation and pretreatment of algae is revealed. The
method includes bioflocculation of precultured algae (Chroococcus sp.) using a pellet …