The distal appendages (DAPs) of centrioles have been proposed to anchor cilia to the plasma
membrane, but their molecular composition, assembly, and exact function in ciliogenesis …

Primary cilia are microtubule-based organelles that detect mechanical and chemical stimuli.
Although cilia house a number of oncogenic molecules (including Smoothened, KRAS, …

Primary cilia are microtubule-based organelles that play important roles in development and
tissue homeostasis. Tau-tubulin kinase-2 (TTBK2) is genetically linked to spinocerebellar …

Poly (ADP-ribose)ylation is a dynamic protein modification that regulates multiple cellular
processes. Here, we describe a system for identifying and characterizing PARylation events …

IQGAP1 is a scaffolding protein previously implicated in adherens junction formation. However,
its role in the establishment or maintenance of tight junctions (TJs) has not been explored…

IQGAP1 is a scaffold protein involved in the assembly of adherens junctions. Our work has
recently revealed a novel role for IQGAP1 in the regulation of tight junctions (TJ) through …

The Abl-interactor (Abi) proteins are involved in the regulation of actin polymerization and
have recently been shown to modulate epidermal growth factor receptor (EGFR) endocytosis. …

Primary cilia are microtubule-based sensory organelles surrounded by membrane. They can
detect mechanical and chemical stimuli. The last few years have uncovered cilia as unique …

Centriole and/or cilia defects are characteristic of cancer cells and have been linked to
cancer cell invasion. However, the mechanistic basis of these effects is unknown. Spindle …

… Los permisos de exploración e investigación afectarán a municipios de Aragón como
Navardún, Urriés, Undués de Lerda, Sos del Rey Católico, Los Pintanos, Isuerre, Lobera, etc. Y en …