Single-cell reconstruction of the early maternal–fetal interface in humans
…, J Henriksson, A Zou, AM Sharkey, B Millar, B Innes… - Nature, 2018 - nature.com
During early human pregnancy the uterine mucosa transforms into the decidua, into which
the fetal placenta implants and where placental trophoblast cells intermingle and …
the fetal placenta implants and where placental trophoblast cells intermingle and …
Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy
GE Lash, B Schiessl, M Kirkley, BA Innes… - Journal of leukocyte …, 2006 - academic.oup.com
Remodeling of uterine spiral arteries is critical for the continuation of a successful pregnancy.
Uterine natural killer (uNK) cells are the predominant leukocyte population in the early …
Uterine natural killer (uNK) cells are the predominant leukocyte population in the early …
Decoding human fetal liver haematopoiesis
…, S Lisgo, J Bacardit, A Fuller, B Millar, B Innes… - Nature, 2019 - nature.com
Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …
Uterine natural killer cells initiate spiral artery remodeling in human pregnancy
A Robson, LK Harris, BA Innes, GE Lash… - The FASEB …, 2012 - Wiley Online Library
Uterine spiral artery remodeling is required for successful human pregnancy; impaired
remodeling is associated with pregnancy complications, including late miscarriage, preeclampsia…
remodeling is associated with pregnancy complications, including late miscarriage, preeclampsia…
Effects of 25-Hydroxyvitamin D3 and 1,25-Dihydroxyvitamin D3 on Cytokine Production by Human Decidual Cells
KN Evans, L Nguyen, J Chan, BA Innes… - Biology of …, 2006 - academic.oup.com
The active form of vitamin D, 1,25-dihydroxyvitamin D 3 (1,25[OH] 2 D 3 ) is a potent
immunomodulatory seco-steroid. We have demonstrated that several components of vitamin D …
immunomodulatory seco-steroid. We have demonstrated that several components of vitamin D …
Uterine natural killer cells and angiogenesis in recurrent reproductive failure
BACKGROUND Increased numbers of phenotypically unusual CD56 bright CD16− uterine
natural killer (uNK) cells have been associated with recurrent reproductive failure. uNK cells …
natural killer (uNK) cells have been associated with recurrent reproductive failure. uNK cells …
The ontogeny of 25-hydroxyvitamin D3 1α-hydroxylase expression in human placenta and decidua
…, KN Evans, MD Kilby, JN Bulmer, BA Innes… - The American journal of …, 2002 - Elsevier
In addition to its classical calciotropic effects, the active form of vitamin D, 1,25-dihydroxyvitamin
D 3 (1,25(OH) 2 D 3 ) is a potent anti-proliferative/immunomodulatory secosteroid. The …
D 3 (1,25(OH) 2 D 3 ) is a potent anti-proliferative/immunomodulatory secosteroid. The …
Inhibition of trophoblast cell invasion by TGFB1, 2, and 3 is associated with a decrease in active proteases
GE Lash, HA Otun, BA Innes, JN Bulmer… - Biology of …, 2005 - academic.oup.com
Invasion of extravillous trophoblast cells into the uterus in human pregnancy is tightly regulated.
The transforming growth factor-beta (TGFB) family has been suggested to play a role in …
The transforming growth factor-beta (TGFB) family has been suggested to play a role in …
Interferon‐γ inhibits extravillous trophoblast cell invasion by a mechanism that involves both changes in apoptosis and protease levels
GE Lash, HA Otun, BA Innes, M Kirkley… - The FASEB …, 2006 - Wiley Online Library
Background: Extravillous trophoblast cell (EVT) invasion of decidua and inner third of the
myometrium is critical for a successful pregnancy. Many decidual factors are likely to play a role …
myometrium is critical for a successful pregnancy. Many decidual factors are likely to play a role …
[HTML][HTML] Altered decidual leucocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy
PJ Williams, JN Bulmer, RF Searle, BA Innes… - …, 2009 - rep.bioscientifica.com
Two experiments using Spanish Merino ewes were conducted to investigate whether the
secretion of prolactin during the follicular phase of the sheep oestrous cycle was involved in the …
secretion of prolactin during the follicular phase of the sheep oestrous cycle was involved in the …