The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin, …

[HTML][HTML] Ketogenic diet in the treatment of cancer–where do we stand?

…, J Tulipan, L Catalano, RG Feichtinger, B Kofler - Molecular …, 2020 - Elsevier
Background Cancer is one of the greatest public health challenges worldwide, and we still
lack complementary approaches to significantly enhance the efficacy of standard anticancer …

Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

…, SA Hobson, D Wynick, T Hoekfelt, B Kofler - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a "classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

[HTML][HTML] No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

…, NM Grüning, RG Feichtinger, H Lehrach, B Kofler… - Oncotarget, 2011 - ncbi.nlm.nih.gov
The Warburg effect describes the circumstance that tumor cells preferentially use glycolysis
rather than oxidative phosphorylation for energy production. It has been reported that this …

Mitochondria: The ketogenic diet—A metabolism-based therapy

…, B Lambert, T Rutherford, W Sperl, B Kofler… - The international journal …, 2015 - Elsevier
Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative
phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. …

[HTML][HTML] Ketogenic diet in cancer therapy

DD Weber, S Aminazdeh-Gohari, B Kofler - Aging (Albany NY), 2018 - ncbi.nlm.nih.gov
Daniela D Weber, Sepideh Aminazdeh-Gohari, Barbara Kofler www. aging-us. com AGIING
2018, Vol. 10, No. 2 www. aging-us. com 164 AGING mostly based on single case reports …

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

…, GW Hacker, C Hauser-Kronberger, B Kofler… - …, 2004 - academic.oup.com
To elucidate the relationship between tumorgenesis and the mitochondrial energy
metabolism in renal neoplasms, we studied three individual enzyme activities of the oxidative …

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

…, M Ratschek, N Schmeller, W Sperl, B Kofler - Clinical Cancer …, 2008 - AACR
Purpose: Many solid tumors exhibit abnormal aerobic metabolism characterized by increased
glycolytic capacity and decreased cellular respiration. Recently, mutations in the nuclear …

[HTML][HTML] Inhibition of neuroblastoma tumor growth by ketogenic diet and/or calorie restriction in a CD1-Nu mouse model

…, JA Mayr, R Lang, D Neureiter, W Sperl, B Kofler - PloS one, 2015 - journals.plos.org
Introduction Neuroblastoma is a malignant pediatric cancer derived from neural crest cells. It
is characterized by a generalized reduction of mitochondrial oxidative phosphorylation. The …

[HTML][HTML] New Aspects on the Structure of Neutrophil Extracellular Traps from Chronic Obstructive Pulmonary Disease and In Vitro Generation

…, W Stoiber, WD Krautgartner, M Klappacher, B Kofler… - PloS one, 2014 - journals.plos.org
Polymorphonuclear neutrophils have in recent years attracted new attention due to their
ability to release neutrophil extracellular traps (NETs). These web-like extracellular structures …