IMM-BCP-01, a patient-derived anti–SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA. 1 and BA. 2

…, BC Heimbach, N Henriquez, C Nicolescu… - Science …, 2022 - science.org
Monoclonal antibodies are an efficacious therapy against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). However, rapid viral mutagenesis led to escape from most of …

[HTML][HTML] Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens …

JM DiMuzio, BC Heimbach, RJ Howanski, JP Dowling… - Vaccine: X, 2021 - Elsevier
Patients who recover from SARS-CoV-2 infections produce antibodies and antigen-specific
T cells against multiple viral proteins. Here, an unbiased interrogation of the anti-viral …

Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail

…, BC Heimbach, N Henriquez, C Nicolescu… - bioRxiv, 2021 - biorxiv.org
Using an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent
COVID-19 patients, we identified three human antibodies that when combined demonstrated …

Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail (preprint)

…, JL Bingaman-Steele, C Nicolescu, BC Heimbach… - 2021 - pesquisa.bvsalud.org
Using an unbiased interrogation of the anti-viral memory B cell repertoire of convalescent
COVID-19 patients, we identified three human antibodies that when combined demonstrated …

[HTML][HTML] Gene expression changes in children with autism

JP Gregg, L Lit, CA Baron, I Hertz-Picciotto, W Walker… - Genomics, 2008 - Elsevier
The objective of this study was to identify gene expression differences in blood differences
in children with autism (AU) and autism spectrum disorder (ASD) compared to general …

Clotting factor levels and the risk of diffuse microvascular bleeding in the massively transfused patient

…, L Baron, E Pavlin, DM Heimbach… - British journal of …, 1987 - Wiley Online Library
Clotting factor activities and coagulation screening tests in 36 massively transfused patients
were measured after every 12 units of blood and whenever diffuse microvascular bleeding (…

Age as a risk factor for burn injury requiring hospitalization during early childhood

PA Simon, RC Baron - Archives of pediatrics & adolescent …, 1994 - jamanetwork.com
Objective: To examine the variation by age in the rates and causes of burn injury requiring
hospitalization during early childhood. Design and Setting: Hospital discharge data and a …

Prophylactic platelet administration during massive transfusion: a prospective, randomized, double-blind clinical study

…, D CIAVARELLA, DM HEIMBACH, L BARON… - Annals of …, 1986 - journals.lww.com
from mucosa, raw wounds, and puncture sites." A pri-mary disorder of hemostasis is suggested,
as standard surgical techniques do not effectively arrest the process. Multiple etiologies …

Tumor-specific human monoclonal antibodies isolated from cancer patients that bind antigens expressed on the outer plasma membrane of cancer cells

B Heimbach, C Swider, H Zhao, P Simon, RK Alpaugh… - Cancer Research, 2015 - AACR
Introduction: Cancer cells express novel antigens that reflect their transformed state and may
engender an antibody response. We hypothesize that some of these auto-antibodies detect …

Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma

DJ Rea, JK Heimbach, CB Rosen, MG Haddock… - Annals of …, 2005 - journals.lww.com
Objective: Compare survival after neoadjuvant therapy and liver transplantation with survival
after resection for patients with hilar CCA. Summary Background Data: We developed a …