Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated
with various neurological complications. Although the mechanism is not fully understood, …

Scarce access to primary samples and lack of efficient protocols to generate oligodendrocytes
(OLs) from human pluripotent stem cells (hPSCs) are hampering our understanding of OL …

The human face represents a combined set of highly heritable phenotypes, but knowledge
on its genetic architecture remains limited, despite the relevance for various fields. A series of …

Schizophrenia is highly heritable, yet its underlying pathophysiology remains largely unknown.
Among the most well-replicated findings in neurobiological studies of schizophrenia are …

The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased
worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with
a wide variety of neurological complications. Even though SARS-CoV-2 is rarely detected in …

Noncoding RNAs have been widely recognized as essential mediators of gene regulation.
However, in contrast to protein‐coding genes, much less is known about the influence of …

The human UBE3A gene, which is essential for normal neurodevelopment, encodes three
Ubiquitin E3 ligase A (UBE3A) protein isoforms. However, the subcellular localization and …

Astrocytes are in constant communication with neurons during the establishment and maturation
of functional networks in the developing brain. Astrocytes release extracellular vesicles (…

CSPG4 Chondroitin Sulfate Proteoglycan 4 Dup15q 15q11-q13 duplication syndrome ESC
Embryonic stem cell EB Embryoid body GWAS Genome wide association study sgRNA …