Rationale: Vascular smooth muscle turnover has important implications for blood vessel repair
and for the development of cardiovascular diseases, yet lack of specific transgenic animal …

Objectives: Matrix metallopeptidase-7 (MMP-7) and osteopontin (OPN) are important
components in the pathophysiology of fibrosis in biliary atresia (BA). There has been much recent …

Ventral body wall (VBW) defects are among the most common congenital malformations, yet
their embryonic origin and underlying molecular mechanisms remain poorly characterised. …

Aim The aim of this study was to report our initial experience using spiral intestinal
lengthening and tailoring (SILT) technique in selected cases of short bowel syndrome (SBS). …

Fibrosis is associated with almost all forms of chronic cardiac and skeletal muscle diseases.
The accumulation of extracellular matrix impairs the contractility of muscle cells contributing …

Objectives To describe the range of concurrent cardiac malformations in biliary atresia (BA)
while providing a functional framework of risk. Methods Demographic and variables were …

Pentalogy of Cantrell (PC) is a rare multi-organ congenital anomaly that impedes ventral
body wall closure and results in diaphragmatic hernia, intra- and pericardial defects. The …

Background Total esophagogastric dissociation (TEGD) has been performed in our institution
since 1994, predating its published description by Bianchi in 1997. Originally it was …

Paediatric chronic pancreatitis (CP) is a rare and debilitating pathology that often requires
invasive diagnostics and therapeutic interventions either to address a primary cause such as a …

Objective The perceived risk of necrotising enterocolitis (NEC) can result in overtreatment of
the otherwise adapting preterm neonate. We aim to develop an assessment tool to aid the …