CD73-dependent adenosine signaling through Adora2b drives immunosuppression in ductal pancreatic cancer
Ductal-derived pancreatic tumors have elevated epithelial and CD8 + GZM + T-cell CD73
expression that confers sensitivity to small-molecule inhibition of CD73 or Adora2b to promote …
expression that confers sensitivity to small-molecule inhibition of CD73 or Adora2b to promote …
Radiofrequency ablation remodels the tumor microenvironment and promotes neutrophil-mediated abscopal immunomodulation in pancreatic cancer
EY Faraoni, BJ O'Brien, LN Strickland, BK Osborn… - Cancer immunology …, 2023 - AACR
… Baylee J. O'Brien … O'Brien, Lincoln N. Strickland, Baron K. Osborn, Victoria Mota, Jarod
Chaney, Constance Lynn Atkins, Putao Cen, Julie Rowe, Jessica Cardenas, Kyle L. …
Chaney, Constance Lynn Atkins, Putao Cen, Julie Rowe, Jessica Cardenas, Kyle L. …
[HTML][HTML] CD73‐generated extracellular adenosine promotes resolution of neutrophil‐mediated tissue injury and restrains metaplasia in pancreatitis
BJ O'Brien, EY Faraoni, LN Strickland, Z Ma… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Pancreatitis is currently the leading cause of gastrointestinal hospitalizations in the US. This
condition occurs in response to abdominal injury, gallstones, chronic alcohol consumption or…
condition occurs in response to abdominal injury, gallstones, chronic alcohol consumption or…
[HTML][HTML] Radiofrequency ablation in combination with CD73 inhibitor AB680 reduces tumor growth and enhances anti-tumor immunity in a syngeneic model of …
EY Faraoni, LN Strickland, BJ O'Brien… - Frontiers in …, 2022 - frontiersin.org
Pancreatic ductal adenocarcinoma presents a 5-year overall survival rate of 11%, placing an
imperative need for the discovery and application of innovative treatments. Radiofrequency …
imperative need for the discovery and application of innovative treatments. Radiofrequency …
Radiofrequency ablation remodels the tumor microenvironment and promotes systemic immunomodulation in pancreatic cancer
EY Faraoni, NC Thosani, B O'Brien, LN Strickland… - bioRxiv, 2022 - biorxiv.org
Background and Aims Pancreatic ductal adenocarcinoma (PDAC) is characterized by
resistance to therapy. A major contributing factor to therapeutic failure is profound desmoplasia …
resistance to therapy. A major contributing factor to therapeutic failure is profound desmoplasia …
CD40 Agonists Reprogram Tumor Associated Macrophages to Reduce Immunosuppression in Pancreatic Ductal Adenocarcinoma
BJ O'Brien - jmsgr.tamhsc.edu
Background: Pancreatic ductal adenocarcinoma (PDAC) is cancer of the ductal cells of the
pancreas and is projected to become the second leading cause of cancer related deaths by …
pancreas and is projected to become the second leading cause of cancer related deaths by …
Flann O'Brien's Speculative Fiction
B Brits - The Parish Review: Journal of Flann O'Brien …, 2013 - parishreview.openlibhums.org
… O’Nolan’s fiction a complicated task. A recurrent mode of narrative organisation in O’Nolan’s
‘Flann O’Brien’ … In O’Brien’s novels we have writers who write books about other writers …
‘Flann O’Brien’ … In O’Brien’s novels we have writers who write books about other writers …
[PDF][PDF] GRADE 6
…, B Neilsen, G Wilkinson, A Hutchison, R O'Brien - carver.org
… Baylee Oswald … Jake O’Neill … Raven O’Brien …
[BOOK][B] Flann O'Brien & Modernism
… peculiar combination of the mundane and the fantastic in O’Brien’s work, a splicing of boredom
… instances of what Brian O’Nolan/Flann O’Brien spontaneously performed – the almost …
… instances of what Brian O’Nolan/Flann O’Brien spontaneously performed – the almost …
Endoscopic Ultrasound-guided Radiofrequency Ablation for Pancreatic Adenocarcinoma
CJ Wray, BOB BSA, P Cen, JH Rowe, EY Faraoni… - 2022 - researchsquare.com
METHODS Prospective review of PDAC patients meeting criteria of resectable tumor
anatomy that underwent NAC chemotherapy plus EUS-RFA followed by pancreatic resection. …
anatomy that underwent NAC chemotherapy plus EUS-RFA followed by pancreatic resection. …