The accessibility and transparency of the cornea permit robust stem cell labeling and in vivo
cell fate mapping. Limbal epithelial stem cells (LSCs) that renew the cornea are traditionally …

Accumulating evidence supports the dogma that the corneal epithelium is regenerated by
stem cells located exclusively in the limbal niche, at the corneal periphery. Accordingly, limbal …

During morphogenesis, preserving tissue boundaries is essential for cell fate regulation. While
embryonic tissues possess high plasticity and repair ability, the questions of whether and …

The cell fate decisions of stem cells (SCs) largely depend on signals from their microenvironment
(niche). However, very little is known about how biochemical niche cues control cell …

A<sc>bstract</sc> Mutations in key transcription factors SOX2 and P63 were linked with
developmental defects and postnatal abnormalities such as corneal opacification, …

Purpose: To investigate the genetic basis for severe visual complaints by Bukharan Jewish
patients with oculopharyngeal muscular dystrophy (OPMD). Methods: Polymerase chain …

Lineage tracing experiments define the origin, fate and behavior of cells in a specific tissue
or organism. This technique has been successfully applied for many decades, revealing …

Purpose To identify the genetic basis for retinitis pigmentosa (RP) in a cohort of Jewish patients
from Caucasia. Methods Patients underwent a detailed ophthalmic evaluation, including …

Our aim was to examine the symptoms and clinical characteristics of visual snow in a group
of 6 patients from a Department of Ophthalmology and a Department of Neurology. Visual …

Introduction. We present a case of a metallic foreign body embedded in the anterior chamber
angle. After standing in close proximity to a construction worker breaking a tile, a 26-year-…