[HTML][HTML] Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells

…, RM Tarradas, B Carmona-Hidalgo… - Redox biology, 2020 - Elsevier
Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis.
Its acting on phospholipid hydroperoxides and its phospholipase-A2 activity are unique …

Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice

B Carmona-Hidalgo, I González-Mariscal… - Phytomedicine, 2021 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in
the Western world, and it is closely associated to obesity, type 2 diabetes mellitus, and …

(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice

I González-Mariscal, B Carmona-Hidalgo… - Pharmacological …, 2021 - Elsevier
Natural cannabidiol ((-)-CBD) and its derivatives have increased interest for medicinal
applications due to their broad biological activity spectrum, including targeting of the cannabinoid …

[HTML][HTML] Peroxiredoxin 6 down-regulation induces metabolic remodeling and cell cycle arrest in HepG2 cells

…, RM Tarradas Valero, B Carmona-Hidalgo… - Antioxidants, 2019 - mdpi.com
Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human
cells. It is the only Prdx acting on phospholipid hydroperoxides possessing two additional …

[HTML][HTML] Monkey adrenal chromaffin cells express α6β4* nicotinic acetylcholine receptors

…, AJ Hone, M Scadden, B Carmona-Hidalgo… - PloS one, 2014 - journals.plos.org
Nicotinic acetylcholine receptors (nAChRs) that contain α6 and β4 subunits have been
demonstrated functionally in human adrenal chromaffin cells, rat dorsal root ganglion neurons, …

[HTML][HTML] Detrimental effect of cannabidiol on the early onset of diabetic nephropathy in male mice

B Carmona-Hidalgo, A García-Martín, E Muñoz… - Pharmaceuticals, 2021 - mdpi.com
Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD).
CBD-based medicinal drugs have been approved for over a lustrum, and a boom in the …

Selectivity of action of pregabalin on Ca2+ channels but not on fusion pore, exocytotic machinery, or mitochondria in chromaffin cells of the adrenal gland

…, A Ruiz-Nuno, B Carmona-Hidalgo… - … of Pharmacology and …, 2012 - ASPET
The present study was planned to investigate the action of pregabalin on voltage-dependent
Ca 2+ channels (VDCCs) and novel targets (fusion pore formed between the secretory …

The firing frequency of spontaneous action potentials and their corresponding evoked exocytosis are increased in chromaffin cells of CCl4‐induced cirrhotic rats with …

…, B CarmonaHidalgo… - Journal of …, 2019 - Wiley Online Library
High catecolamine plasma levels because of sympathetic nervous system over‐activity
contribute to cirrhosis progression. The aim of this study was to investigate whether chromaffin …

Human native Cav1 channels in chromaffin cells: contribution to exocytosis and firing of spontaneous action potentials

…, N Garcia-Magro, B Carmona-Hidalgo… - European Journal of …, 2017 - Elsevier
The present study was performed to evaluate the Ca v 1 channel subtypes expressed in
human chromaffin cells and the role that these channels play in exocytosis and cell excitability. …

Fisiología de las células cromafines de la glándula adrenal de rata en situación control y en la cirrosis hepática: Contribución a la cirrosis hepática inducida por CI4C

BC Hidalgo - 2017 - dialnet.unirioja.es
La cirrosis hepática es una patología asociada a una serie de manifestaciones clínicas,
considerada como una vía común en numerosos tipos de lesiones hepáticas crónicas. …