Inflammatory bowel disease (IBD) is a heterogeneous state of chronic intestinal inflammation
of unknown cause encompassing Crohn’s disease (CD) and ulcerative colitis (UC). IBD …

Inflammatory bowel disease (IBD) is an umbrella term for the chronic immune-mediated
idiopathic inflammation of the gastrointestinal tract, manifesting as Crohn’s disease (CD) or …

Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …

Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC),
is a heterogeneous state of chronic intestinal inflammation with no exact known cause. …

In addition to triggering humoral responses, conventional B cells have been described in
vitro to cross‐present exogenous antigens activating naïve CD8 + T cells. Nevertheless, the …

Lifestyle and nutritional habits represent critical triggers for immune-metabolic disorders,
including nonalcoholic fatty liver disease (NAFLD) and atherosclerosis. 1 Time-restricted …

Nuclear envelope lamin A/C proteins are a major component of the mammalian nuclear
lamina, a dense fibrous protein meshwork located in the nuclear interior. Lamin A/C proteins …

The mechanisms by which lamin A/C in CD4 + T‐cells control intestinal homeostasis and
can cause inflammatory bowel disease (IBD) are unknown. Here, we explore lamin A/C in a …

Aging is characterized by gradual immune dysfunction and increased disease risk. Genomic
instability is considered central to the aging process, but the underlying mechanisms of …

Quantification of naïve CD4 T cell activation, proliferation, and differentiation to T helper 1 (Th1)
cells is a useful way to assess the role played by T cells in an immune response. This …