User profiles for Behrang Mahjani
 | Behrang MahjaniDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY Verified email at mssm.edu Cited by 2907 |
[PDF][PDF] Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
Rare coding variation provides insight into the genetic architecture and phenotypic context of autism
Some individuals with autism spectrum disorder (ASD) carry functional mutations rarely
observed in the general population. We explored the genes disrupted by these variants from …
observed in the general population. We explored the genes disrupted by these variants from …
Genetics of obsessive-compulsive disorder
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades of …
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades of …
Association of genetic and environmental factors with autism in a 5-country cohort
Importance The origins and development of autism spectrum disorder (ASD) remain
unresolved. No individual-level study has provided estimates of additive genetic, maternal, and …
unresolved. No individual-level study has provided estimates of additive genetic, maternal, and …
Maternal effects as causes of risk for obsessive-compulsive disorder
Background While genetic variation has a known impact on the risk for obsessive-compulsive
disorder (OCD), there is also evidence that there are maternal components to this risk. …
disorder (OCD), there is also evidence that there are maternal components to this risk. …
[HTML][HTML] Comorbidities in autism spectrum disorder and their etiologies
Individuals with autism spectrum disorder (ASD), in addition to the core features of the
disease, experience a higher burden of co-occurring medical conditions. This study sought to …
disease, experience a higher burden of co-occurring medical conditions. This study sought to …
Association between mental health and reproductive system disorders in women: a systematic review and meta-analysis
Importance Reproductive system and mental health disorders are commonly comorbid in
women. Although the causes of this overlap remain elusive, evidence suggests potential …
women. Although the causes of this overlap remain elusive, evidence suggests potential …
Rare coding variation illuminates the allelic architecture, risk genes, cellular expression patterns, and phenotypic context of autism
Individuals with autism spectrum disorder (ASD) or related neurodevelopmental disorders (NDDs)
often carry disruptive mutations in genes that are depleted of functional variation in …
often carry disruptive mutations in genes that are depleted of functional variation in …
[HTML][HTML] Heritable variation, with little or no maternal effect, accounts for recurrence risk to autism spectrum disorder in Sweden
Background Autism spectrum disorder (ASD) has both genetic and environmental origins,
including potentially maternal effects. Maternal effects describe the association of one or more …
including potentially maternal effects. Maternal effects describe the association of one or more …
Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk
We present the largest exome sequencing study to date focused on rare variation in autism
spectrum disorder (ASD) (n=35,584). Integrating de novo and case-control variation with an …
spectrum disorder (ASD) (n=35,584). Integrating de novo and case-control variation with an …