The genetic architecture of phenotypic diversity in the Betta fish (Betta splendens)

W Zhang, H Wang, DYC Brandt, B Hu, J Sheng… - Science …, 2022 - science.org
The Betta fish displays a remarkable variety of phenotypes selected during domestication.
However, the genetic basis underlying these traits remains largely unexplored. Here, we …

UV filter ethylhexyl salicylate affects cardiovascular development by disrupting lipid metabolism in zebrafish embryos

…, S Guo, S Zeng, C Ye, M Wang, Z Anwar, B Hu… - Science of The Total …, 2023 - Elsevier
Ethylhexyl salicylate (EHS) is an organic UV filter commonly used in sunscreens to protect
people from the UV radiation. The widespread use of EHS will enter the aquatic environment …

[HTML][HTML] Seasonal and inter-annual community structure characteristics of zooplankton driven by water environment factors in a sub-lake of Lake Poyang, China

B Hu, X Hu, X Nie, X Zhang, N Wu, Y Hong, HM Qin - PeerJ, 2019 - peerj.com
Background Sub-lakes are important for the maintenance of the ecosystem integrity of Lake
Poyang, and zooplankton play an important role in its substance and energy flow. Methods A …

[HTML][HTML] Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3

H Sun, C Wang, B Hu, X Gao, T Zou, Q Luo… - Signal transduction and …, 2021 - nature.com
Intercellular cross-talk plays important roles in cancer progression and metastasis. Yet how
these cancer cells interact with each other is still largely unknown. Exosomes released by …

[HTML][HTML] Insulin-like growth factor 1-induced enolase 2 deacetylation by HDAC3 promotes metastasis of pancreatic cancer

…, M Xue, D Xu, F Yang, D Fu, C Wang, B Hu… - Signal transduction and …, 2020 - nature.com
Enolase 2 (ENO2) is a key glycolytic enzyme in the metabolic process of glycolysis, but its
potential function in pancreatic ductal adenocarcinoma (PDAC) is unclear. In this study, we …

Inhibition of EGFR overcomes acquired Lenvatinib resistance driven by STAT3–ABCB1 signaling in hepatocellular carcinoma

B Hu, T Zou, W Qin, X Shen, Y Su, J Li, Y Chen… - Cancer Research, 2022 - AACR
HCC cells acquire resistance to lenvatinib by activating the EGFR–STAT3–ABCB1 pathway,
identifying combined treatment with erlotinib as a strategy to overcome acquired resistance …

The impact of aquaculture system on the microbiome and gut metabolome of juvenile Chinese softshell turtle (Pelodiscus sinensis)

X Ding, F Jin, J Xu, S Zhang, D Chen, B Hu, Y Hong - IMeta, 2022 - Wiley Online Library
The commercial aquatic animal microbiome may markedly affect the successful host's
farming in various aquaculture systems. However, very little was known about it. Here, two …

[HTML][HTML] Subpopulations of cancer-associated fibroblasts link the prognosis and metabolic features of pancreatic ductal adenocarcinoma

B Hu, C Wu, H Mao, H Gu, H Dong, J Yan… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Cancer-associated fibroblasts (CAFs) are a vital constituent of the tumor
microenvironment (TME) and have several activities, but the effect of CAF heterogeneity on the …

STMN1 upregulation mediates hepatocellular carcinoma and hepatic stellate cell crosstalk to aggravate cancer by triggering the MET pathway

R Zhang, X Gao, J Zuo, B Hu, J Yang, J Zhao… - Cancer …, 2020 - Wiley Online Library
STMN1 has been regarded as an oncogene and its upregulation is closely associated with
malignant behavior and poor prognosis in multiple cancers. However, the detailed functions …

[HTML][HTML] Comparison of nutritional quality and volatile flavor compounds among bighead carp from three aquaculture systems

B Hu, J Zhou, H Qiu, X Lai, J Li, D Wu, J Sheng… - Saudi Journal of …, 2021 - Elsevier
To explore the differences in the nutritional quality of the muscles of bighead carp from
different environments and aquaculture systems, we investigated three types of water bodies …