Impact of toll-like receptor 4 signaling in necrotizing enterocolitis: the state of the science
B Mihi, M Good - Clinics in perinatology, 2019 - perinatology.theclinics.com
Since the emergence of early eukaryotic organisms, a plethora of sophisticated defense
mechanisms has evolved to protect the host from invading pathogens and to ensure species …
mechanisms has evolved to protect the host from invading pathogens and to ensure species …
[HTML][HTML] Current and future methods of probiotic therapy for necrotizing enterocolitis
…, SG Volpe, Z Dumbauld, N Purayil, B Mihi… - Frontiers in …, 2023 - frontiersin.org
Necrotizing enterocolitis (NEC) is a complex intestinal disease that primarily affects premature
neonates. Given its significant mortality and morbidity, there is an urgent need to develop …
neonates. Given its significant mortality and morbidity, there is an urgent need to develop …
[HTML][HTML] Stem cell-derived models of viral infections in the gastrointestinal tract
WE Lanik, MA Mara, B Mihi, CB Coyne, M Good - Viruses, 2018 - mdpi.com
Studies on the intestinal epithelial response to viral infection have previously been limited
by the absence of in vitro human intestinal models that recapitulate the multicellular …
by the absence of in vitro human intestinal models that recapitulate the multicellular …
[PDF][PDF] Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration
B Mihi, Q Gong, LS Nolan, SE Gale, M Goree, E Hu… - Cell Reports …, 2021 - cell.com
Necrotizing enterocolitis (NEC) is a deadly intestinal inflammatory disorder that primarily
affects premature infants and lacks adequate therapeutics. Interleukin (IL)-22 plays a critical …
affects premature infants and lacks adequate therapeutics. Interleukin (IL)-22 plays a critical …
T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death
B Belaid, L Lamara Mahammad, B Mihi… - Journal of leukocyte …, 2022 - academic.oup.com
The immune system plays a crucial role in the response against severe acute respiratory
syndrome coronavirus 2 with significant differences among patients. The study investigated the …
syndrome coronavirus 2 with significant differences among patients. The study investigated the …
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures
Although they globally cause viral gastroenteritis in children, astroviruses are understudied
due to the lack of well-defined animal models. While murine astroviruses (muAstVs) …
due to the lack of well-defined animal models. While murine astroviruses (muAstVs) …
Lactotrehalose, an analog of trehalose, increases energy metabolism without promoting Clostridioides difficile infection in mice
…, JR Crowley, MR Heitmeier, AI Stothard, B Mihi… - Gastroenterology, 2020 - Elsevier
Background & Aims Trehalose is a disaccharide that might be used in the treatment of
cardiometabolic diseases. However, trehalose consumption promotes the expansion of …
cardiometabolic diseases. However, trehalose consumption promotes the expansion of …
[HTML][HTML] Digital dermatitis in cattle is associated with an excessive innate immune response triggered by the keratinocytes
W Refaai, R Ducatelle, P Geldhof, B Mihi… - BMC veterinary …, 2013 - Springer
Background Digital Dermatitis (DD) is a common disease of dairy cows, the pathogenesis of
which is still not clear. This study examined some host responses associated with the typical …
which is still not clear. This study examined some host responses associated with the typical …
Helicobacter pullorum Cytolethal Distending Toxin Targets Vinculin and Cortactin and Triggers Formation of Lamellipodia in Intestinal Epithelial Cells
C Varon, I Mocan, B Mihi… - The Journal of …, 2014 - academic.oup.com
Helicobacter pullorum, a bacterium initially isolated from poultry, has been associated with
human digestive disorders. However, the factor responsible for its cytopathogenic effects on …
human digestive disorders. However, the factor responsible for its cytopathogenic effects on …
[HTML][HTML] Indole-3-carbinol–dependent aryl hydrocarbon receptor signaling attenuates the inflammatory response in experimental necrotizing enterocolitis
LS Nolan, B Mihi, P Agrawal, Q Gong, JM Rimer… - …, 2021 - journals.aai.org
Necrotizing enterocolitis (NEC) causes significant morbidity and mortality in premature
infants; therefore, the identification of therapeutic and preventative strategies against NEC …
infants; therefore, the identification of therapeutic and preventative strategies against NEC …