Rapid input-restricted change in gene expression is an important aspect of synaptic plasticity
requiring complex mechanisms of post-transcriptional mRNA trafficking and regulation. …

A localized transcriptome at the synapse facilitates synapse-, stimulus- and transcript-specific
local protein synthesis in response to neuronal activity. While enzyme-mediated mRNA …

To facilitate intercellular communication, cells release nano-sized, extracellular vesicles (EVs)
to transfer biological cargo to both local and distant sites. EVs are enriched in tetraspanins…

The SH-SY5Y culture system is a convenient neuronal model with the potential to elaborate
human/primate-specific transcription networks and pathways related to human cognitive …

Intracellular messenger RNA (mRNA) traffic and translation must be highly regulated, both
temporally and spatially, within eukaryotic cells to support the complex functional partitioning. …

Background MicroRNAs (miRNAs) play a pivotal role in coordinating messenger RNA (mRNA)
transcription and stability in almost all known biological processes, including the …

Most eukaryotic mRNAs accommodate alternative sites of poly(A) addition in the 3’ untranslated
region in order to regulate mRNA function. Here, we present a systematic analysis of 3’ …

Tetraspanin CD9 is generally considered to be a metastasis suppressor, with decreased
levels associated with progression and metastasis in many advanced stage cancers. Little is …

While the cytoplasmic function of microRNA (miRNA) as post-transcriptional regulators of
mRNA has been the subject of significant research effort, their activity in the nucleus is less …

In the version of this article initially published, a Supplementary Fig. 6f was cited in the last
paragraph of the Results. No such panel exists; the citation has been deleted. The error has …