Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

W Li, V Tran, I Shaked, B Xue, T Moore, R Lightle… - Elife, 2021 - elifesciences.org
Mosaic inactivation of CCM2 in humans causes cerebral cavernous malformations (CCMs)
containing adjacent dilated blood-filled multi-cavernous lesions. We used CRISPR-Cas9 …

[HTML][HTML] The BTK inhibitor, Bgb-3111, is safe, tolerable, and highly active in patients with relapsed/refractory B-cell malignancies: initial report of a phase 1 first-in …

…, B Dimovski, E Hedrick, J Yang, L Wang, L Luo, L Xue… - Blood, 2015 - Elsevier
Introduction: Bruton's tyrosine kinase (BTK) is a downstream intermediary of B cell receptor (BCR)
signaling. As revealed by ibrutinib, disruption of BCR signaling results in significant …

Analyst forecasting during COVID-19 pandemic

R Hao, J Xue, LNB Yau, C Zhang - Managerial Auditing Journal, 2022 - emerald.com
Purpose This study aims to examine the characteristics of financial analysts’ earnings
forecasts after COVID-19 outbroke in the USA. Specifically, the authors examine how financial …

Audit Delay During Regulatory Relief of Reporting Deadline: Evidence from Hong Kong

R Hao, J Xue, B Yau - Available at SSRN 4791873, 2024 - papers.ssrn.com
Considering the adverse impact of the COVID-19 pandemic and the subsequent travel
restrictions imposed by the governments of Hong Kong and China on audit process, Hong Kong …

Prediction for 2-year vision outcomes using early morphologic and functional responses in the comparison of age-related macular degeneration treatments trials

K Xue, P Hua, MG Maguire, E Daniel, GJ Jaffe… - Ophthalmology …, 2023 - Elsevier
Objective To predict 2-year visual acuity (VA) responses to anti-VEGF therapy, using early
morphologic and functional responses in patients with neovascular age-related macular …

Steps toward determination of the size and structure of the broad-line region in active galactic nuclei. XV. Long-term optical monitoring of NGC 5548

…, JY Wei, BJ Wilkes, H Wu, SJ Xue… - The Astrophysical …, 1999 - iopscience.iop.org
We present the results of 3 yr of ground-based observations of the Seyfert 1 galaxy NGC 5548,
which, combined with previously reported data, yield optical continuum and broad-line H …

Machine learning on DNA-encoded libraries: a new paradigm for hit finding

K McCloskey, EA Sigel, S Kearnes, L Xue… - Journal of Medicinal …, 2020 - ACS Publications
DNA-encoded small molecule libraries (DELs) have enabled discovery of novel inhibitors
for many distinct protein targets of therapeutic value. We demonstrate a new approach …

Multiwavelength observations of short-timescale variability in NGC 4151. IV. Analysis of multiwavelength continuum variability

…, BJ Wilkes, H Wu, J Wurster, SJ Xue… - The Astrophysical …, 1996 - dash.harvard.edu
This paper combines data from the three preceding papers in order to analyze the multi-wave-band
variability and spectral energy distribution of the Seyfert I galaxy NGC 4151 during …

A new, faint population of X-ray transients

…, P Tozzi, C Vignali, J Wang, Y Xue… - Monthly Notices of …, 2017 - academic.oup.com
We report on the detection of a remarkable new fast high-energy transient found in the Chandra
Deep Field-South, robustly associated with a faint (m R = 27.5 mag, z ph ∼ 2.2) host in …

Polar soils exhibit distinct patterns in microbial diversity and dominant phylotypes

…, X Liu, BC Ferrari, L Malard, C Liang, K Xue… - Soil Biology and …, 2022 - Elsevier
The polar regions, comprising the Antarctic, Arctic and Tibetan Plateau, represent the most
extreme environments on Earth. Soils across the polar regions harbor diverse microorganisms…