A visual pathway for skylight polarization processing in Drosophila

BJ Hardcastle, JJ Omoto, P Kandimalla, BCM Nguyen… - Elife, 2021 - elifesciences.org
Many insects use patterns of polarized light in the sky to orient and navigate. Here, we
functionally characterize neural circuitry in the fruit fly, Drosophila melanogaster, that conveys …

[PDF][PDF] Evolution of biological image stabilization

BJ Hardcastle, HG Krapp - Current Biology, 2016 - cell.com
The use of vision to coordinate behavior requires an efficient control design that stabilizes the
world on the retina or directs the gaze towards salient features in the surroundings. With a …

[PDF][PDF] Inhibitory interactions and columnar inputs to an object motion detector in Drosophila

MF Keleş, BJ Hardcastle, C Städele, Q Xiao, MA Frye - Cell reports, 2020 - cell.com
The direction-selective T4/T5 cells innervate optic-flow processing projection neurons in the
lobula plate of the fly that mediate the visual control of locomotion. In the lobula, visual …

[PDF][PDF] Spike burst coding of translatory optic flow and depth from motion in the fly visual system

KD Longden, M Wicklein, BJ Hardcastle, SJ Huston… - Current Biology, 2017 - cell.com
Many animals use the visual motion generated by traveling straight—the translatory optic
flow—to successfully navigate obstacles: near objects appear larger and to move more quickly …

[HTML][HTML] Serotonergic modulation of visual neurons in Drosophila melanogaster

…, KM Myers Gschweng, BJ Hardcastle… - PLoS …, 2020 - journals.plos.org
Sensory systems rely on neuromodulators, such as serotonin, to provide flexibility for
information processing as stimuli vary, such as light intensity throughout the day. Serotonergic …

[HTML][HTML] Impact of walking speed and motion adaptation on optokinetic nystagmus-like head movements in the blowfly Calliphora

KD Longden, A Schützenberger, BJ Hardcastle… - Scientific Reports, 2022 - nature.com
The optokinetic nystagmus is a gaze-stabilizing mechanism reducing motion blur by rapid
eye rotations against the direction of visual motion, followed by slower syndirectional eye …

Passive inertial damping improves high-speed gaze stabilization in hoverflies

BJ Hardcastle, K Bierig, FJH Heras, KD Longden… - bioRxiv, 2021 - biorxiv.org
Gaze stabilization reflexes reduce motion blur and simplify the processing of visual information
by keeping the eyes level. These reflexes typically depend on estimates of the rotational …

Spike interval coding of translatory optic flow and depth from motion in the fly visual system

KD Longden, M Wicklein, BJ Hardcastle, SJ Huston… - bioRxiv, 2016 - biorxiv.org
Many animals use the visual motion generated by travelling straight, the translatory optic
flow, to successfully navigate obstacles: near objects appear larger and to move more quickly …

Ocellar contributions to gaze control: a behavioural linear systems analysis in the blowfly

BJ Hardcastle, DA Schwyn, KD Longden… - … of Neuroethology (ICN …, 2012 - frontiersin.org
In flying insects the stabilization of gaze aids visual processing by reducing motion blur, for
instance, and facilitating self-motion estimation. The gaze control system in blowflies makes …

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

…, PJ Coffey, JP Chapple, AJ Hardcastle… - Human molecular …, 2017 - academic.oup.com
Ciliary trafficking defects are the underlying cause of many ciliopathies, including Retinitis
Pigmentosa (RP). Anterograde intraflagellar transport (IFT) is mediated by kinesin motor …