Purpose : Radical nephrectomy has traditionally been preferred to partial nephrectomy in
patients with localized renal cell cancer because of its simplicity and established cancer control…

Purpose : Compared to radical nephrectomy, partial nephrectomy better preserves renal
parenchyma and function. Although several clinical factors may impact renal function after …

Collective cell contractions that generate global tissue deformations are a signature feature
of animal movement and morphogenesis. However, the origin of collective contractility in …

BACKGROUND: Although nephrectomy cures most localized renal cancers, this oncologic
benefit may be outweighed by the renal functional costs of such an approach. In this study, …

BACKGROUND: Partial nephrectomy (PN) has been associated with improved overall
survival (OS) in select cohorts with localised renal masses when compared to radical …

Objective To report changes in grade and stage between initial diagnostic and repeat
biopsies or resection for urothelial carcinoma (UTUC) and investigate the consequences for …

OBJECTIVES: Elective partial nephrectomy (PN) in patients with cT1b renal tumors is
relatively unstudied. Most surgeons currently only perform radical nephrectomy (RN) in this …

Although collar cells are conserved across animals and their closest relatives, the
choanoflagellates, little is known about their ancestry, their subcellular architecture, or how they …

Oocytes are large cells that develop into an embryo upon fertilization 1 . As interconnected
germ cells mature into oocytes, some of them grow—typically at the expense of others that …

Inspired by the patterns of multicellularity in choanoflagellates, the closest living relatives of
animals, we quantify the biophysical processes underlying the morphogenesis of rosette …