The COVID-19 pandemic has demonstrated the need for massively-parallel, cost-effective
tests monitoring viral spread. Here we present SARSeq, saliva analysis by RNA sequencing, …

Protein phosphorylation regulates key processes in all organisms. In Gram-positive bacteria,
protein arginine phosphorylation plays a central role in protein quality control by regulating …

In Gram-positive bacteria, the McsB protein arginine kinase is central to protein quality
control, labeling aberrant molecules for degradation by the ClpCP protease. Despite its …

During a pandemic, mitigation as well as protection of system-critical or vulnerable institutions
requires massively parallel, yet cost-effective testing to monitor the spread of agents such …

During a pandemic, mitigation as well as protection of system-critical or vulnerable institutions
requires massive parallel, yet cost effective testing to monitor the spread of agents such as …

Arginine protein kinases regulate bacterial signaling cascades through phosphorylation of
key arginine residues. Crystal structures of the kinase McsB provide the first glimpse of how …

Protein arginine phosphorylation is an emerging post-translational modification found in
gram-positive bacteria. Here, the phospho-arginine (pArg) mark serves as degradation signal …

RT-qPCR-based diagnostic tests play important roles in combating virus-caused pandemics
such as Covid-19. However, their dependence on sophisticated equipment and the …

RT-qPCR-based diagnostic tests play important roles in combating virus-caused pandemics
such as Covid-19. However, their dependence on sophisticated equipment and the …

McQ is a SARS-CoV-2 quantification assay that couples early-stage barcoding with high-throughput
sequencing to enable multiplexed processing of thousands of samples. McQ is …