[HTML][HTML] Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation

B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …

[HTML][HTML] Decline of humoral and cellular immune responses against SARS-CoV-2 6 months after full BNT162b2 vaccination in hospital healthcare workers

B Bonnet, H Chabrolles, C Archimbaud… - Frontiers in …, 2022 - frontiersin.org
Clinical trials and real-world evidence on COVID-19 vaccines have shown their effectiveness
against severe disease and death but the durability of protection remains unknown. We …

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells

…, W Chaara, K El Soufi, B Bonnet… - Proceedings of the …, 2018 - National Acad Sciences
T follicular helper (Tfh) and regulatory (Tfr) cells are terminally differentiated cells found in
germinal centers (GCs), specialized secondary lymphoid organ structures dedicated to …

Low-dose IL-2 induces regulatory T cell–mediated control of experimental food allergy

B Bonnet, J Vigneron, B Levacher… - The Journal of …, 2016 - journals.aai.org
Regulatory T cells (Tregs) are pivotal for maintenance of immune self-tolerance and also
regulate immune responses to exogenous Ags, including allergens. Both decreased Treg …

PHM for railway system—A case study on the health assessment of the point machines

…, D Siegel, S Chang, P Dersin, B Bonnet… - … IEEE Conference on …, 2012 - ieeexplore.ieee.org
Point machines are used for operating railway turn outs and are considered as critical track
elements in railway assets. Failures in the point machine's mechanism cause delays, …

A new method for measurement of left atrial volumes using 64-slice spiral computed tomography: comparison with two-dimensional echocardiographic techniques

…, S Ragot, J Mergy, D Herpin, B Bonnet… - International journal of …, 2009 - Elsevier
BACKGROUND: Left atrial (LA) volume, is related to cardiovascular morbidity. LA enlargement
is usually assessed using trans-thoracic echocardiography (TTE). The association of …

[HTML][HTML] Renal dysfunction improves risk stratification and may call for a change in the management of intermediate-and high-risk acute pulmonary embolism: results …

…, G Serzian, F Ecarnot, N Falvo, E Kalbacher, B Bonnet… - Critical Care, 2021 - Springer
Background Renal dysfunction influences outcomes after pulmonary embolism (PE). We
aimed to determine the incremental value of adding renal dysfunction, defined by estimated …

Incidence, predictors, and impact on six-month mortality of three different definitions of contrast-induced acute kidney injury after coronary angiography

…, D Ducloux, M Chatot, M Badoz, B Bonnet… - The American Journal of …, 2018 - Elsevier
We assessed incidence, predictors, and impact on 6-month mortality of contrast-induced
acute kidney injury (CI-AKI) after coronary angiography with or without percutaneous coronary …

[HTML][HTML] Hypercoagulability in critically ill patients with COVID 19, an observational prospective study

…, AF Sapin, K Grapin, JM Liteaudon, B Evrard, B Bonnet… - Plos one, 2022 - journals.plos.org
Objective COVID 19 is often associated with hypercoagulability and thromboembolic (TE)
events. The aim of this study was to assess the characteristics of hypercoagulability and its …

Association of nitrogen balance trajectories with clinical outcomes in critically ill COVID-19 patients: A retrospective cohort study

…, P Couhault, F Kinda, G Laurichesse, B Bonnet… - Clinical Nutrition, 2022 - Elsevier
Background & aims The intensity and duration of the catabolic phase in COVID-19 patients
can differ between survivors and non-survivors. The purpose of the study was to assess the …