User profiles for Benjamin D. Hale

Benjamin David Hale

IMSB, ETH Zurich
Verified email at biol.ethz.ch
Cited by 223

[HTML][HTML] Regional protein expression in human Alzheimer's brain correlates with disease severity

…, S Patassini, N Rustogi, I Riba-Garcia, BD Hale… - Communications …, 2019 - nature.com
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently affects
36 million people worldwide with no effective treatment available. Development of AD …

[HTML][HTML] Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma

…, S Goetze, R Wegmann, Y Festl, Y Severin, BD Hale… - Nature Cancer, 2023 - nature.com
Multiple myeloma (MM) is a plasma cell malignancy defined by complex genetics and
extensive patient heterogeneity. Despite a growing arsenal of approved therapies, MM remains …

Multifunctional mRNA-based CAR T cells display promising antitumor activity against glioblastoma

…, P Roth, S Pascolo, U Sahin, S Lee, BD Hale… - Clinical Cancer …, 2022 - AACR
Purpose: Most chimeric antigen receptor (CAR) T-cell strategies against glioblastoma have
demonstrated only modest therapeutic activity and are based on persistent gene modification …

Multiplexed high-throughput immune cell imaging reveals molecular health-associated phenotypes

Y Severin, BD Hale, J Mena, D Goslings, BM Frey… - Science …, 2022 - science.org
Phenotypic plasticity is essential to the immune system, yet the factors that shape it are not
fully understood. Here, we comprehensively analyze immune cell phenotypes including …

[HTML][HTML] Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis

…, C Dördelmann, M van Oostrum, BD Hale… - Nature …, 2023 - nature.com
Myelofibrosis is a hematopoietic stem cell disorder belonging to the myeloproliferative
neoplasms. Myelofibrosis patients frequently carry driver mutations in either JAK2 or Calreticulin (…

The CDF Run IIb silicon detector: Design, preproduction, and performance

…, D Benjamin, D Bisello, G Bolla, D Bortoletto… - Nuclear Instruments and …, 2006 - Elsevier
A new silicon microstrip detector was designed by the CDF collaboration for the proposed
high-luminosity operation of the Tevatron pp collider (Run IIb). The detector is radiation-…

CDF run IIb silicon: design and testing

…, S Behari, D Benjamin, D Bisello… - … on Nuclear Science, 2004 - ieeexplore.ieee.org
The various generations of Silicon Vertex Detectors (SVX, SVX', SVXII) for Collider Detector
at Fermilab (CDF) at the Fermilab Tevatron have been fundamental tools for heavy-flavor …

Sensors for the CDF Run2b silicon detector

…, S Behari, D Benjamin, D Bisello… - … on Nuclear Science, 2004 - ieeexplore.ieee.org
We describe the characteristics of silicon microstrip sensors fabricated by Hamamatsu
Photonics for the CDF Run 2b silicon detector. A total of 953 sensors, including 117 prototype …

CDF Run IIb silicon detector: Electrical performance and deadtime-less operation

…, S Behari, D Benjamin, D Bisello… - … on Nuclear Science, 2004 - ieeexplore.ieee.org
The main building block and readout unit of the planned CDF Run IIb silicon detector is a "stave,"
a highly integrated mechanical, thermal, and electrical structure. One of its …

Monitoring of ammonia and fine particulates downwind of broiler houses

…, CW Ritz, LA Harper, BD Hale… - … , Rhode Island, June …, 2008 - elibrary.asabe.org
Air emissions from animal feeding operations have become a growing concern for producers
and their neighbors. Much work has been done to quantify emission rates; however, little …