User profiles for Benjamin J. Heil

Benjamin J Heil

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 186

Reproducibility standards for machine learning in the life sciences

BJ Heil, MM Hoffman, F Markowetz, SI Lee… - Nature …, 2021 - nature.com
To make machine-learning analyses in the life sciences more computationally reproducible,
we propose standards based on data, model and code publication, programming best …

Protein classification using modified n-grams and skip-grams

SMA Islam, BJ Heil, CM Kearney, EJ Baker - Bioinformatics, 2018 - academic.oup.com
Motivation Classification by supervised machine learning greatly facilitates the annotation of
protein characteristics from their primary sequence. However, the feature generation step in …

[HTML][HTML] MousiPLIER: A Mouse Pathway-Level Information Extractor Model

S Zhang, BJ Heil, W Mao, M Chikina, CS Greene… - bioRxiv, 2023 - ncbi.nlm.nih.gov
High throughput gene expression profiling is a powerful approach to generate hypotheses on
the underlying causes of biological function and disease. Yet this approach is limited by its …

The Effects of Nonlinear Signal on Expression-Based Prediction Performance

BJ Heil, J Crawford, CS Greene - bioRxiv, 2022 - biorxiv.org
Those building predictive models from transcriptomic data are faced with two conflicting
perspectives. The first, based on the inherent high dimensionality of biological systems, …

[HTML][HTML] The Field-Dependent Nature of PageRank Values in Citation Networks

BJ Heil, CS Greene - bioRxiv, 2023 - ncbi.nlm.nih.gov
The value of scientific research can be easier to assess at the collective level than at the level
of individual contributions. Several journal-level and article-level metrics aim to measure …

Hetnet connectivity search provides rapid insights into how biomedical entities are related

…, M Zietz, V Rubinetti, K Kloster, BJ Heil… - …, 2023 - academic.oup.com
Background Hetnets, short for “heterogeneous networks,” contain multiple node and relationship
types and offer a way to encode biomedical knowledge. One such example, Hetionet, …

Neural Nets Are Not All You Need: Evaluating the Effects of Deep Learning on Transcriptomic Analysis

BJ Heil - 2023 - search.proquest.com
Technologies for quantifying biology have undergone significant advances in the past few
decades, leading to datasets rapidly increasing in size and complexity. At the same time, deep …

[HTML][HTML] The effect of non-linear signal in classification problems using gene expression

BJ Heil, J Crawford, CS Greene - PLOS Computational Biology, 2023 - journals.plos.org
Those building predictive models from transcriptomic data are faced with two conflicting
perspectives. The first, based on the inherent high dimensionality of biological systems, …

E-AHPBA–ESSO–ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy

…, P Starlinger, BVM Dasari, J Heil… - British journal of …, 2023 - academic.oup.com
Background Posthepatectomy liver failure (PHLF) contributes significantly to morbidity and
mortality after liver surgery. Standardized assessment of preoperative liver function is crucial …

[BOOK][B] Philosophy of mind: A contemporary introduction

J Heil - 2019 - taylorfrancis.com
… The right of John Heil to be identified as author of this work has been asserted by him in
accordance with sections 77 and 78 of the Copyright, Designs and Patents Act 1988. …