[HTML][HTML] Pharmacokinetics of intravenous, intramuscular, oral, and transdermal administration of flunixin meglumine in pre-wean piglets

…, SM Rajewski, JF Coetzee, BK Schneider… - Frontiers in Veterinary …, 2020 - frontiersin.org
Castration and tail-docking of pre-wean piglets are common procedures that are known to
induce pain and would benefit from pain mitigation. Flunixin meglumine (FM) is a non-…

[HTML][HTML] Breakthrough: a first-in-class virtual simulator for dose optimization of ACE inhibitors in translational cardiovascular medicine

BK Schneider, J Ward, S Sotillo, C Garelli-Paar… - Scientific Reports, 2023 - nature.com
The renin–angiotensin–aldosterone-systems (RAAS) play a central role in the pathophysiology
of congestive heart failure (CHF), justifying the use of angiotensin converting enzyme …

Nonlinear mixed‐effects pharmacokinetic modeling of the novel COX‐2 selective inhibitor vitacoxib in dogs

J Wang, BK Schneider, P Sun, X Gong… - Journal of veterinary …, 2019 - Wiley Online Library
The objective of this study was to develop a nonlinear mixed‐effects model of vitacoxib
disposition kinetics in dogs after intravenous (IV), oral (PO), and subcutaneous (SC) dosing. Data …

Optimal scheduling of bevacizumab and pemetrexed/cisplatin dosing in non‐small cell lung cancer

BK Schneider, A Boyer, J Ciccolini… - CPT …, 2019 - Wiley Online Library
Bevacizumab‐pemetrexed/cisplatin ( BEV ‐ PEM / CIS ) is a first‐line therapeutic for
advanced nonsquamous non‐small cell lung cancer. Bevacizumab potentiates PEM / CIS …

[HTML][HTML] Pharmacokinetic modeling of ceftiofur sodium using non-linear mixed-effects in healthy beagle dogs

J Wang, BK Schneider, J Xue, P Sun, J Qiu… - Frontiers in Veterinary …, 2019 - frontiersin.org
Ceftiofur (CEF) sodium is a third-generation broad-spectrum cephalosporin commonly used
in an extra-label manner in dogs for the treatment of respiratory and urinary system infections…

[HTML][HTML] Comparison of standard electrocardiography and smartphone-based electrocardiography recorded at two different anatomic locations in healthy meat and …

JS Smith, JL Ward, BK Schneider, FL Smith… - Frontiers in Veterinary …, 2020 - frontiersin.org
Smartphones present multiple applications for ambulatory practice. One of the newer
technologies is smartphone-based electrocardiography (ECG). While this technology has been …

[HTML][HTML] In vitro Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs

…, GR Buettner, BA Wagner, BK Schneider… - Frontiers in veterinary …, 2019 - frontiersin.org
Background: High-dose, pharmacological ascorbate (P-AscH − ) is preferentially cytotoxic to
human cancer cells in vitro. Investigations on the efficacy of P-AscH − as an adjuvant …

The spatial relationship between the low-income housing tax credit program and industrial air pollution

DK Goplerud, SG Gensheimer, BK Schneider… - Cityscape, 2022 - JSTOR
Housing is a key social determinant of health, but programs that create affordable housing
may unintentionally concentrate residents in neighborhoods with unhealthy exposures, such …

Breakthrough: A First-In-Class Virtual Simulator for Dose Optimization of ACE Inhibitors in Veterinary Cardiology

BK Schneider, J Ward, S Sotillo, C Garelli-Paar… - bioRxiv, 2022 - biorxiv.org
The human and canine renin-angiotensin-aldosterone-systems (RAAS) play a central role
in the pathophysiology of congestive heart failure (CHF), justifying the use of angiotensin …

[HTML][HTML] Non-linear mixed-effects pharmacokinetic modeling of the novel COX-2 selective inhibitor vitacoxib in cats

J Wang, BK Schneider, H Xiao, J Qiu… - Frontiers in Veterinary …, 2020 - frontiersin.org
The objective of this study was to develop a non-linear mixed-effects (NLME) model to
describe the disposition kinetics of vitacoxib in cats following intravenous (IV) and oral (PO) (…