[HTML][HTML] A review of the therapeutic potential of recently developed G protein-biased kappa agonists
KL Mores, BR Cummins, RJ Cassell… - Frontiers in …, 2019 - frontiersin.org
Between 2000 and 2005 several studies revealed that morphine is more potent and exhibits
fewer side effects in beta-arrestin 2 knockout mice. These findings spurred efforts to develop …
fewer side effects in beta-arrestin 2 knockout mice. These findings spurred efforts to develop …
Modulating β-arrestin 2 recruitment at the δ-and μ-opioid receptors using peptidomimetic ligands
μ-Opioid receptor agonists provide potent and effective acute analgesia; however, their
therapeutic window narrows considerably upon repeated administration, such as required for …
therapeutic window narrows considerably upon repeated administration, such as required for …
[HTML][HTML] The Meta-Position of Phe4 in Leu-Enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors
As tool compounds to study cardiac ischemia, the endogenous δ-opioid receptors (δOR)
agonist Leu 5 -enkephalin and the more metabolically stable synthetic peptide (d-Ala 2 , d-Leu …
agonist Leu 5 -enkephalin and the more metabolically stable synthetic peptide (d-Ala 2 , d-Leu …
[HTML][HTML] Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities
…, RJ Cassell, KL Mores, AM Gutridge, BR Cummins… - Molecules, 2021 - mdpi.com
The δ-opioid receptor (δOR) holds great potential as a therapeutic target. Yet, clinical drug
development, which has focused on δOR agonists that mimic the potent and selective tool …
development, which has focused on δOR agonists that mimic the potent and selective tool …
Community lay rescuer automated external defibrillation programs: key state legislative components and implementation strategies: a summary of a decade of …
Cardiovascular disease is a leading cause of death for adults ≥40 years of age. The American
Heart Association (AHA) estimates that sudden cardiac arrest is responsible for about …
Heart Association (AHA) estimates that sudden cardiac arrest is responsible for about …
A spectrographically grounded scale for evaluating reading expressiveness
RG Benjamin, PJ Schwanenflugel… - Reading Research …, 2013 - Wiley Online Library
This study evaluated the validity of a new scale for assessing children's reading fluency skill
called the Comprehensive Oral Reading Fluency Scale ( CORFS ). The CORFS consists of …
called the Comprehensive Oral Reading Fluency Scale ( CORFS ). The CORFS consists of …
[BOOK][B] The maintenance of Spanish by Mexicano children and its function in their school lives
R Benjamin - 1993 - search.proquest.com
INFORMATION TO USERS Page 1 INFORMATION TO USERS This manuscript has been
reproduced from the microfilm master. UMI films the text directly from the original or copy …
reproduced from the microfilm master. UMI films the text directly from the original or copy …
[HTML][HTML] Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors
…, RS Benjamin, RE Brown, P Anderson, R Kurzrock - PloS one, 2014 - journals.plos.org
Background Ewing's sarcoma (ES) and desmoplastic small round cell tumors (DSRCT) are
small round blue cell tumors driven by an N-terminal containing EWS translocation. Very few …
small round blue cell tumors driven by an N-terminal containing EWS translocation. Very few …
Persistent TTX-Resistant Na+ Current Affects Resting Potential and Response to Depolarization in Simulated Spinal Sensory Neurons
RI Herzog, TR Cummins… - Journal of …, 2001 - journals.physiology.org
Small dorsal root ganglion (DRG) neurons, which include nociceptors, express multiple
voltage-gated sodium currents. In addition to a classical fast inactivating tetrodotoxin-sensitive (…
voltage-gated sodium currents. In addition to a classical fast inactivating tetrodotoxin-sensitive (…
Adolescent impulsivity phenotypes characterized by distinct brain networks
The impulsive behavior that is often characteristic of adolescence may reflect underlying
neurodevelopmental processes. Moreover, impulsivity is a multi-dimensional construct, and it is …
neurodevelopmental processes. Moreover, impulsivity is a multi-dimensional construct, and it is …