[HTML][HTML] Neuronal ensemble-specific DNA methylation strengthens engram stability

K Gulmez Karaca, J Kupke, DVC Brito, B Zeuch… - Nature …, 2020 - nature.com
Memories are encoded by memory traces or engrams, represented within subsets of neurons
that are synchronously activated during learning. However, the molecular mechanisms that …

[HTML][HTML] Where have I been? Where should I go? Spatial working memory on a radial arm maze in a rat model of depression

SH Richter, B Zeuch, K Lankisch, P Gass, D Durstewitz… - PloS one, 2013 - journals.plos.org
Disturbances in cognitive functioning are among the most debilitating problems experienced
by patients with major depression. Investigations of these deficits in animals help to extend …

Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation

KG Karaca, DVC Brito, B Zeuch… - Neurobiology of learning …, 2018 - Elsevier
MeCP2 is required both during postnatal neurodevelopment and throughout the adult life
for brain function. Although it is well accepted that MeCP2 in the maturing nervous system is …

Mimicking age-associated Gadd45γ dysregulation results in memory impairments in young adult mice

DVC Brito, J Kupke, KG Karaca, B Zeuch… - Journal of …, 2020 - Soc Neuroscience
Age-related memory loss is observed across multiple mammalian species and preferentially
affects hippocampus-dependent memory. Memory impairments are characterized by …

Development of screening assays and discovery of initial inhibitors of pneumococcal peptidoglycan deacetylase PgdA

…, S Buckenmaier, F Stevenson-Jones, B Zeuch… - Biochemical …, 2011 - Elsevier
The essential cell wall peptidoglycan is the target of several components of the innate immune
system and its disruption results in lysis of invading bacteria. The pathogen Streptococcus …

Environmental enrichment ameliorates depressive-like symptoms in young rats bred for learned helplessness

SH Richter, B Zeuch, MA Riva, P Gass… - Behavioural brain …, 2013 - Elsevier
The incidence of major depression is known to be influenced by both genetic and environmental
factors. In the current study, we therefore set out to investigate depressive-like behavior …

Engram reactivation during memory retrieval predicts long-term memory performance in aged mice

KG Karaca, DVC Brito, J Kupke, B Zeuch… - Neurobiology of …, 2021 - Elsevier
Age-related cognitive decline preferentially targets long-lasting episodic memories that
require intact hippocampal function. Memory traces (or engrams) are believed to be encoded …

Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice

DVC Brito, KG Karaca, J Kupke, F Mudlaff, B Zeuch… - Neurobiology of …, 2020 - Elsevier
Aging is associated with the progressive decay of cognitive function. Hippocampus-dependent
processes, such as the formation of spatial memory, are particularly vulnerable to aging. …

[BOOK][B] Benjam. Schmolkens Weil. Past. Prim. und Insp. der Evangelischen Kirchen und Schulen vor Schweidnitz. Gott-geheiligtes Buß-Opfer Christlicher …

B Schmolck - 1745 - books.google.com
… Werde mir ein Brunn in deinem Wor te, der da quillt ins ewige Les ben. Zeuch doch meine
See le mit allen ihren Begierden kräfftig zu Dir, daß sie an deinen Worten hange. Gieb ihr das …

[BOOK][B] Benjam. Schmolckens... Gott-geheiligtes Buß-Opfer Christlicher Communicanten: nebst andern geistreichen Betrachtungen ans Licht gestellet

B Schmolck - 1736 - books.google.com
… Werde mir ein Brunn in deinem Wor te, der da quillt ins efvige Leben. Zeuch doch meine
Seele mit allen ihren Begierden Fräfftig zu Dir, daß sie an deinen Worten hange. Gieb ihr das …