User profiles for Benjamin tenOever
Benjamin tenOeverNew York University Verified email at NYUlangone.org Cited by 17110 |
Triggering the interferon antiviral response through an IKK-related pathway
Rapid induction of type I interferon expression, a central event in establishing the innate
antiviral response, requires cooperative activation of numerous transcription factors. Although …
antiviral response, requires cooperative activation of numerous transcription factors. Although …
[HTML][HTML] Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
There is an urgent need to create novel models using human disease-relevant cells to study
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology and to facilitate …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology and to facilitate …
[HTML][HTML] RNA viruses and the host microRNA machinery
BR Tenoever - Nature Reviews Microbiology, 2013 - nature.com
Gene silencing by small RNAs (sRNAs) occurs in all three domains of life. In recent years, our
appreciation of the diverse functions of sRNAs has increased, and we have identified roles …
appreciation of the diverse functions of sRNAs has increased, and we have identified roles …
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery
…, S Lomvardas, V Zachariou, BR Tenoever - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae of …
infection can result in prolonged pathologies collectively referred to as post-acute sequalae of …
Immune memory from SARS-CoV-2 infection in hamsters provides variant-independent protection but still allows virus transmission
SARS-CoV-2 has caused morbidity and mortality across the globe. As the virus spreads,
new variants are arising that show enhanced capacity to bypass preexisting immunity. To …
new variants are arising that show enhanced capacity to bypass preexisting immunity. To …
SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
…, M Panis, D Sachs, RA Albrecht, BR tenOever - BioRxiv, 2020 - biorxiv.org
One of the greatest threats to humanity is the emergence of a pandemic virus. Among those
with the greatest potential for such an event include influenza viruses and coronaviruses. In …
with the greatest potential for such an event include influenza viruses and coronaviruses. In …
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients
with COVID-19 by producing a cytokine storm, which correlates with increased lethality. …
with COVID-19 by producing a cytokine storm, which correlates with increased lethality. …
SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells
…, DD Ho, GS Pitt, RE Schwartz, BR TenOever… - Circulation …, 2022 - Am Heart Assoc
Background: Increasing evidence suggests that cardiac arrhythmias are frequent clinical
features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to bradycardia…
features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to bradycardia…
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication
…, DA Matthews, BR tenOever… - Science …, 2022 - science.org
Multiple coronaviruses have emerged independently in the past 20 years that cause lethal
human diseases. Although vaccine development targeting these viruses has been …
human diseases. Although vaccine development targeting these viruses has been …
MicroRNA-mediated species-specific attenuation of influenza A virus
…, MH Lorini, MA Chua, J Steel, BR TenOever - Nature …, 2009 - nature.com
Influenza A virus leads to yearly epidemics and sporadic pandemics. Present prophylactic
strategies focus on egg-grown, live, attenuated influenza vaccines (LAIVs), in which …
strategies focus on egg-grown, live, attenuated influenza vaccines (LAIVs), in which …