The peroxiredoxins define an emerging family of peroxidases able to reduce hydrogen
peroxide and alkyl hydroperoxides with the use of reducing equivalents derived from thiol-…

Clara cell protein (CC16 or CC10) is a 15.8‐kDa protein secreted all along the tracheobronchial
tree and especially in the terminal bronchioles where Clara cells are localized. Even …

Using two-dimensional electrophoresis, we have recently identified in human bronchoalveolar
lavage fluid a novel protein, termed B166, with a molecular mass of 17 kDa. Here, we …

Peroxiredoxin 5 (PRDX5) was the last member to be identified among the six mammalian
peroxiredoxins. It is also the unique atypical 2-Cys peroxiredoxin in mammals. Like the other …

Peroxiredoxins are an ubiquitous family of peroxidases widely distributed among prokaryotes
and eukaryotes. Peroxiredoxin 5, which is the last discovered mammalian member, was …

Human peroxiredoxin 5 (PRDX5) catalyzes different peroxides reduction by enzymatic
substitution mechanisms. Enzyme oxidation caused an increase in Trp84 fluorescence, allowing …

Inflammation is a pathophysiological response to infection or tissue damage during which
high levels of reactive oxygen and nitrogen species are produced by phagocytes to kill …

In basal conditions, thyroid epithelial cells produce moderate amounts of reactive oxygen
species (ROS) that are physiologically required for thyroid hormone synthesis. They are not …

Peroxiredoxin 5 is a thioredoxin peroxidase ubiquitously expressed in mammalian tissues.
Peroxiredoxin 5 can be addressed intracellularly to mitochondria, peroxisomes, the cytosol …

Clara cell secretory protein (CC16, CC10, or CCSP), the major secretory protein of the
Clara cell, presents several biologic properties, suggesting that it may play a protective role …