Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2,
and reported to be efficient in Chinese COV-19 patients. We evaluate the effect of …

Viruses are obligate parasites of Eukarya, Archaea and Bacteria. Acanthamoeba polyphaga
mimivirus (APMV) is the largest known virus; it grows only in amoeba and is visible under …

During a study following a pneumonia outbreak in 1992, a microorganism growing in amoebae
and resembling a small Gram-positive coccus (Fig. 1A) was isolated from the water of a …

Background . Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass
spectrometry accurately identifies both selected bacteria and bacteria in select clinical …

We recently reported the discovery and preliminary characterization of Mimivirus, the largest
known virus, with a 400-nanometer particle size comparable to mycoplasma. Mimivirus is a …

Background Whipple's disease is a systemic bacterial infection, but to date no isolate of the
bacterium has been established in subculture, and no strain of this bacterium has been …

In a preliminary clinical study, we observed that the combination of hydroxychloroquine and
azithromycin was effective against SARS-CoV-2 by shortening the duration of viral load in …

Background We need an effective treatment to cure COVID-19 patients and to decrease
virus carriage duration. Methods We conducted an uncontrolled, non-comparative, …

Metagenomics revolutionized the understanding of the relations among the human microbiome,
health and diseases, but generated a countless number of sequences that have not …

Background In France, the combination hydroxychloroquine (HCQ) and azithromycin (AZ) is
used in the treatment of COVID-19. Methods We retrospectively report on 1061 SARS-CoV-…