Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Objective To update evidence‐based recommendations for the treatment of patients with
ankylosing spondylitis ( AS ) and nonradiographic axial spondyloarthritis (SpA). Methods We …

We report a multi-omic resource generated by applying quantitative trait locus (xQTL) analyses
to RNA sequence, DNA methylation and histone acetylation data from the dorsolateral …

Vasculitis, inflammation of the vessel wall, can result in mural destruction with hemorrhage,
aneurysm formation, and infarction, or intimal-medial hyperplasia and subsequent stenosis …

Here we use deep sequencing to identify sources of variation in mRNA splicing in the
dorsolateral prefrontal cortex (DLPFC) of 450 subjects from two aging cohorts. Hundreds of …

Importance Most previous genome-wide association studies (GWAS) of depression have used
data from individuals of European descent. This limits the understanding of the underlying …

Objectives : The authors sought to evaluate the plaque-modifying effects of low-dose colchicine
therapy plus optimal medical therapy (OMT) in patients post-acute coronary syndrome (…

Long non-coding RNA (lncRNA) genes have well-established and important impacts on
molecular and cellular functions. However, among the thousands of lncRNA genes, it is still a …

Proper food waste management has been a growing concern for densely populated urban
cities, like Singapore. The current practice of incineration is questionable in terms of …

The most common clinical syndromes that cause nasal congestion are allergic rhinitis,
vasomotor rhinitis, chronic sinusitis, and upper respiratory viral infections (common colds). Nasal …