Important building blocks for the synthesis of drugs or natural products are found in Mannich
bases and their derivatives. Modern variants of the Mannich reaction that expand the …

Multicomponent reactions (MCRs) are by far the most successful class of reactions leading
to high structural diversity and molecular complexity through a single transformation. As part …

Isocyanide‐based multicomponent reactions (IMCRs) can be considered one of the
breakthrough reaction classes of the last century. Moreover, asymmetric IMCRs have recently …

Metal-free 1,3-dipolar cycloaddition reactions have proven to be a powerful tool for the
assembly of key heterocycles, in particular diversely functionalized 1,2,3-triazoles. A number of …

Triple‐T trick! Traceless tosylhydrazone‐based triazole formation is readily achieved by
reacting primary amines with functional α,α‐dichlorotosylhydrozones under ambient conditions. …

A simple and efficient metal-free methodology for the regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles
has been developed by applying a novel inverse electron-demand-1,3-…

Systemic acquired resistance ( SAR ) prepares infected plants for faster and stronger
defense activation upon subsequent attacks. SAR requires an information relay from primary …

Synchronizing organocatalysis! By targeting structural and stereochemical complexity with
organocascade reactions, distinct catalysts can form molecular frameworks in an …

Fungal unspecific peroxygenases (UPOs) represent an enzyme class catalysing versatile
oxyfunctionalisation reactions on a broad substrate scope. They are occurring as secreted, …

The antioxidant and enzyme inhibitory potential of fifteen cycloartane-type triterpenes’
potentials were investigated using different assays. In the phosphomolybdenum method, …