Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a
number of neurological conditions compared with healthy controls (HC) and is a candidate …

The interrelationships between pathological processes and emerging clinical phenotypes in
Alzheimer's disease (AD) are important yet complicated to study, because the brain is a …

See Chard and Miller (doi: 10.1093/brain/awv354 ) for a scientific commentary on this article
. Grey matter atrophy is common in multiple sclerosis. However, in contrast with other …

The characterization of gray matter morphology of individual brains is an important issue in
neuroscience. Graph theory has been used to describe cortical morphology, with networks …

Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral
amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and …

Importance Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD).
Understanding the association between amyloid aggregation and cognitive manifestation in …

Background Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of
Alzheimer’s disease (AD) and is considered to result from neurodegeneration. T-tau levels, …

We investigated whether the functional connectivity and network topology in 69 Alzheimer's
disease (AD), 48 behavioral variant of frontotemporal dementia (bvFTD) patients, and 64 …

BACKGROUND Low cerebrospinal fluid (CSF) amyloid-β 1–42 (Aβ 1–42) concentrations
indicate amyloid plaque accumulation in the brain, a pathological hallmark of Alzheimer …