User profiles for Betul Kirdar

Betul Kirdar

Verified email at boun.edu.tr
Cited by 3088

[HTML][HTML] Genome-Wide Transcriptional Response of Saccharomyces cerevisiae to Stress-Induced Perturbations

…, A Cankorur-Cetinkaya, B Kirdar - … in Bioengineering and …, 2016 - frontiersin.org
Cells respond to environmental and/or genetic perturbations in order to survive and proliferate.
Characterization of the changes after various stimuli at different -omics levels is crucial to …

[HTML][HTML] Doxorubicin induces an extensive transcriptional and metabolic rewiring in yeast cells

…, ME Karabekmez, S Eraslan, B Kırdar - Scientific reports, 2018 - nature.com
Doxorubicin is one of the most effective chemotherapy drugs used against solid tumors in
the treatment of several cancer types. Two different mechanisms, (i) intercalation of …

Integration of metabolome data with metabolic networks reveals reporter reactions

…, KR Patil, ZI Önsan, KÖ Ülgen, B Kirdar… - Molecular systems …, 2006 - embopress.org
Interpreting quantitative metabolome data is a difficult task owing to the high connectivity in
metabolic networks and inherent interdependency between enzymatic regulation, metabolite …

Mathematical description of ethanol fermentation by immobilised Saccharomyces cerevisiae

G Birol, P Doruker, B Kirdar, Zİ Önsan, K Ülgen - Process Biochemistry, 1998 - Elsevier
Fermentation characteristics of Saccharomyces cerevisiae ATCC 9763 immobilised in Ca-alginate
gel beads have been investigated in a stirred batch system at 2, 4, 8, 10% (w/v) initial …

[HTML][HTML] Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains

…, K Van Eunen, JC Ewald, JJ Heijnen, B Kirdar… - Nature …, 2010 - nature.com
The field of systems biology is often held back by difficulties in obtaining comprehensive,
high-quality, quantitative data sets. In this paper, we undertook an interlaboratory effort to …

Evaluation of industrial Saccharomyces cerevisiae strains for ethanol production from biomass

…, L Lama, B Nicolaus, SG Oliver, ET Oner, B Kirdar - Biomass and …, 2012 - Elsevier
Five industrial Saccharomyces cerevisiae strains were evaluated for their suitability for strain
improvement for future use in ethanol production processes. Principal components analysis …

Analysis of the CFTR gene in Turkish cystic fibrosis patients: identification of three novel mutations (3172delAC, P1013L and M1028I)

…, H Cokugras, N Akcakaya, M Apak, LC Tsui, B Kirdar - Human genetics, 1998 - Springer
In order to determine the spectrum of cystic fibrosis (CF) mutations in the Turkish population,
a complete coding region of the cystic fibrosis transmembrane conductance regulator (CFTR…

[HTML][HTML] Biomass composition: the “elephant in the room” of metabolic modelling

D Dikicioglu, B Kırdar, SG Oliver - Metabolomics, 2015 - Springer
Genome-scale stoichiometric models, constrained to optimise biomass production are often
used to predict mutant phenotypes. However, for Saccharomyces cerevisiae, the …

Effect of wastewater composition on archaeal population diversity

AT Akarsubasi, O Ince, B Kirdar, NA Oz, D Orhon… - Water research, 2005 - Elsevier
Distribution and occurrence of Archaea and methanogenic activity in a laboratory scale,
completely mixed anaerobic reactor treating pharmaceutical wastewaters were investigated and …

Ethanol production and fermentation characteristics of recombinant Saccharomyces cerevisiae strains grown on starch

G Birol, Zİ Önsan, B Kırdar, SG Oliver - Enzyme and microbial technology, 1998 - Elsevier
The production of ethanol from starch has been investigated in three genetically modified
Saccharomyces cerevisiae strains (YPG/AB, YPG/MM, and YPB-G). Two of the three strains …