The genetic and epigenetic landscape of the Arabidopsis centromeres

…, BW Abramson, A Schmücker, T Mandáková, B Jamge… - Science, 2021 - science.org
INTRODUCTION The centromeres of eukaryotic chromosomes assemble the multiprotein
kinetochore complex and thereby position attachment to the spindle microtubules, allowing …

The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A. W

A Osakabe, B Jamge, E Axelsson, SA Montgomery… - Nature Cell …, 2021 - nature.com
Mobile transposable elements (TEs) not only participate in genome evolution but also
threaten genome integrity. In healthy cells, TEs that encode all of the components that are …

Histone variants shape chromatin states in Arabidopsis

B Jamge, ZJ Lorković, E Axelsson, A Osakabe… - Elife, 2023 - elifesciences.org
How different intrinsic sequence variations and regulatory modifications of histones
combine in nucleosomes remain unclear. To test the importance of histone variants in the …

[HTML][HTML] The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana

…, R Yelagandula, Y Tarutani, D Jiang, L Jing, B Jamge… - Genome biology, 2017 - Springer
Background Gene bodies of vertebrates and flowering plants are occupied by the histone
variant H3.3 and DNA methylation. The origin and significance of these profiles remain largely …

[PDF][PDF] The Polycomb repressive complex 2 deposits H3K27me3 and represses transposable elements in a broad range of eukaryotes

…, A Fridrich, CH Cho, T Chaumier, B Jamge… - Current Biology, 2023 - cell.com
The mobility of transposable elements (TEs) contributes to evolution of genomes. Their
uncontrolled activity causes genomic instability; therefore, expression of TEs is silenced by host …

[PDF][PDF] Antimicrobial activity of Azadirachta indica (Neem) against pathogenic microorganisms

RR Raut, AR Sawant, BB Jamge - J. Acad. Ind. Res, 2014 - researchgate.net
Plants have been a source of herbal remedies throughout the history of mankind. Various
medicinal plants have been used for years in daily life to treat diseases all over the world. In …

Transcriptional activity is shaped by the chromatin landscapes in Arabidopsis

B Jamge, ZJ Lorković, E Axelsson, R Yelagandula… - bioRxiv, 2022 - biorxiv.org
How histone variants and histone modifications shape nucleosome-mediated transcriptional
repression, and how transcriptional activity shapes the enrichment of histone modifications …

Diversification of chromatin organization in eukaryotes

B Jamge, F Berger - Current Opinion in Cell Biology, 2022 - Elsevier
Our knowledge of the chromatin landscape and its regulation was originally discovered
using yeast and a limited number of animals models. A wealth of studies in model plants now …

Transposons repressed by H3K27me3 were co-opted as cis-regulatory elements of H3K27me3 controlled protein coding genes during evolution of plants

…, F Romani, S Wu, T Kowar, R Lintermann, B Jamge… - bioRxiv, 2022 - biorxiv.org
The mobility of transposable elements (TEs) contributes to evolution of genomes 1 , 2 .
Meanwhile, their uncontrolled activity causes genomic instability and therefore expression of TEs …

Repression of CHROMOMETHYLASE 3 prevents epigenetic collateral damage in Arabidopsis

RK Papareddy, K Páldi, AD Smolka, P Hüther… - elife, 2021 - elifesciences.org
DNA methylation has evolved to silence mutagenic transposable elements (TEs) while
typically avoiding the targeting of endogenous genes. Mechanisms that prevent DNA …