Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake

…, DM Ruiz, KY Wang, BS Sayal, S González Zapata… - Nature …, 2021 - nature.com
TUG tethering proteins bind and sequester GLUT4 glucose transporters intracellularly, and
insulin stimulates TUG cleavage to translocate GLUT4 to the cell surface and increase …

An insulin-stimulated proteolytic mechanism links energy expenditure with glucose uptake

…, H Li, DM Ruiz, KY Wang, BS Sayal, S Hirabara… - bioRxiv, 2019 - biorxiv.org
Mechanisms to coordinately regulate energy expenditure and glucose uptake into muscle
and fat cells are not well described. Insulin stimulates glucose uptake by causing site-specific …

CBVD grown HfO2 on TiN for high-precision MIM capacitor

R Rani, W Maudez, R Sayal, R Rai, S Kumar… - Physica B: Condensed …, 2023 - Elsevier
HfO 2 thin films with three different thickness (∼10 nm, ∼30 nm & ∼ 50 nm) were deposited
on TiN/Si by Chemical Beam Vapor Deposition (CBVD) technique with combinatorial …

[HTML][HTML] Focus: Organelles: Glut4 storage vesicles: Specialized organelles for regulated trafficking

…, SG DeVries, D Ruiz, B Sayal… - The Yale journal of …, 2019 - ncbi.nlm.nih.gov
Fat and muscle cells contain a specialized, intracellular organelle known as the GLUT4
storage vesicle (GSV). Insulin stimulation mobilizes GSVs, so that these vesicles fuse at the cell …

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

…, F Castellino, B Flach, BC Lin, S O'Connell… - Science, 2022 - science.org
… These efficacy data supported the FDA’s EUA of mRNA-1273 for the prevention of COVID-19
in adults (7). The mRNA-1273 vaccine has been shown to be highly effective in the elderly …

Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial

…, F Castellino, B Flach, BC Lin, S O'Connell… - Science translational …, 2023 - science.org
… a vaccine with established efficacy, a CoP could serve as a primary endpoint for immunobridging
of vaccine efficacy to a target population that was not included in the randomized trial(s

[BOOK][B] Human rights law and practice

JK Das - 2022 - books.google.com
… In this case, the Court held that “adultery” is the voluntary sexual intercourse of a married
person with a person other than the offender’s husband or wife but Section 497 of the Indian …