User profiles for Bianca Dumitrascu
Bianca DumitrascuColumbia University Verified email at columbia.edu Cited by 519 |
[HTML][HTML] In silico tissue generation and power analysis for spatial omics
As spatially resolved multiplex profiling of RNA and proteins becomes more prominent, it is
increasingly important to understand the statistical power available to test specific …
increasingly important to understand the statistical power available to test specific …
Deep learning for bioimage analysis in developmental biology
Deep learning has transformed the way large and complex image datasets can be processed,
reshaping what is possible in bioimage analysis. As the complexity and size of bioimage …
reshaping what is possible in bioimage analysis. As the complexity and size of bioimage …
[HTML][HTML] Sparse multi-output Gaussian processes for online medical time series prediction
Background For real-time monitoring of hospital patients, high-quality inference of patients’
health status using all information available from clinical covariates and lab test results is …
health status using all information available from clinical covariates and lab test results is …
netNMF-sc: leveraging gene–gene interactions for imputation and dimensionality reduction in single-cell expression analysis
Single-cell RNA-sequencing (scRNA-seq) enables high-throughput measurement of RNA
expression in single cells. However, because of technical limitations, scRNA-seq data often …
expression in single cells. However, because of technical limitations, scRNA-seq data often …
[HTML][HTML] Optimal marker gene selection for cell type discrimination in single cell analyses
Single-cell technologies characterize complex cell populations across multiple data modalities
at unprecedented scale and resolution. Multi-omic data for single cell gene expression, in …
at unprecedented scale and resolution. Multi-omic data for single cell gene expression, in …
Pg-ts: Improved thompson sampling for logistic contextual bandits
B Dumitrascu, K Feng… - Advances in neural …, 2018 - proceedings.neurips.cc
We address the problem of regret minimization in logistic contextual bandits, where a learner
decides among sequential actions or arms given their respective contexts to maximize …
decides among sequential actions or arms given their respective contexts to maximize …
[HTML][HTML] Hypergraph factorization for multi-tissue gene expression imputation
Integrating gene expression across tissues and cell types is crucial for understanding the
coordinated biological mechanisms that drive disease and characterize homoeostasis. …
coordinated biological mechanisms that drive disease and characterize homoeostasis. …
[HTML][HTML] Causal network inference from gene transcriptional time-series response to glucocorticoids
Gene regulatory network inference is essential to uncover complex relationships among gene
pathways and inform downstream experiments, ultimately enabling regulatory network re-…
pathways and inform downstream experiments, ultimately enabling regulatory network re-…
Statistical tests for detecting variance effects in quantitative trait studies
Motivation Identifying variants, both discrete and continuous, that are associated with
quantitative traits, or QTs, is the primary focus of quantitative genetics. Most current methods are …
quantitative traits, or QTs, is the primary focus of quantitative genetics. Most current methods are …
End-to-end training of deep probabilistic CCA on paired biomedical observations
Medical pathology images are visually evaluated by experts for disease diagnosis, but the
connection between image features and the state of the cells in an image is typically unknown…
connection between image features and the state of the cells in an image is typically unknown…