[HTML][HTML] COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
…, M Meister, C Veith, AW Boots, BP Hennig… - The EMBO …, 2020 - embopress.org
The SARS ‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID ‐19 …
public health and urgently demands for increasing our understanding of COVID ‐19 …
Human haematopoietic stem cell lineage commitment is a continuous process
Blood formation is believed to occur through stepwise progression of haematopoietic stem
cells (HSCs) following a tree-like hierarchy of oligo-, bi-and unipotent progenitors. However, …
cells (HSCs) following a tree-like hierarchy of oligo-, bi-and unipotent progenitors. However, …
[HTML][HTML] Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
…, J Loske, C Klasa, T Krieger, BP Hennig… - Nature …, 2021 - nature.com
In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular diseases are
major risk factors for critical disease progression. However, the underlying causes and the …
major risk factors for critical disease progression. However, the underlying causes and the …
Large-scale low-cost NGS library preparation using a robust Tn5 purification and tagmentation protocol
BP Hennig, L Velten, I Racke, CS Tu… - G3: Genes …, 2018 - academic.oup.com
Efficient preparation of high-quality sequencing libraries that well represent the biological
sample is a key step for using next-generation sequencing in research. Tn5 enables fast, …
sample is a key step for using next-generation sequencing in research. Tn5 enables fast, …
[PDF][PDF] Deletion and point mutations of PTHLH cause brachydactyly type E
E Klopocki, BP Hennig, K Dathe, R Koll… - The American Journal of …, 2010 - cell.com
Autosomal-dominant brachydactyly type E (BDE) is a congenital limb malformation
characterized by small hands and feet predominantly as a result of shortened metacarpals and …
characterized by small hands and feet predominantly as a result of shortened metacarpals and …
Chd1 chromatin remodelers maintain nucleosome organization and repress cryptic transcription
BP Hennig, K Bendrin, Y Zhou, T Fischer - EMBO reports, 2012 - embopress.org
Chromatin organization is essential for defining transcription units and maintaining genomic
integrity in eukaryotes. In this study, we found that deletion of the Schizosaccharomyces …
integrity in eukaryotes. In this study, we found that deletion of the Schizosaccharomyces …
SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
…, H Winter, M Meister, C Veith, AW Boots, BP Hennig… - BioRxiv, 2020 - biorxiv.org
The SARS-CoV-2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID-19 …
public health and urgently demands for increasing our understanding of COVID-19 …
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast
Cryptic transcription is widespread and generates a heterogeneous group of RNA molecules
of unknown function. To improve our understanding of cryptic transcription, we investigated …
of unknown function. To improve our understanding of cryptic transcription, we investigated …
[HTML][HTML] Mesomelic dysplasia Kantaputra type is associated with duplications of the HOXD locus on chromosome 2q
PN Kantaputra, E Klopocki, BP Hennig… - European journal of …, 2010 - nature.com
Mesomelic dysplasia Kantaputra type (MDK) is characterized by marked mesomelic shortening
of the upper and lower limbs originally described in a Thai family. To identify the cause of …
of the upper and lower limbs originally described in a Thai family. To identify the cause of …