[HTML][HTML] Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Most transcriptome-wide association studies (TWASs) so far focus on European ancestry and
lack diversity. To overcome this limitation, we aggregated genome-wide association study (…
lack diversity. To overcome this limitation, we aggregated genome-wide association study (…
The effects of organic food on human health: a systematic review and meta-analysis of population-based studies
B Jiang, J Pang, J Li, L Mi, D Ru, J Feng, X Li… - Nutrition …, 2023 - academic.oup.com
Context Although the nutritional composition of organic food has been thoroughly researched,
there is a dearth of published data relating to its impact on human health. Objective This …
there is a dearth of published data relating to its impact on human health. Objective This …
[HTML][HTML] Construction and application of polygenic risk scores in autoimmune diseases
Genome-wide association studies (GWAS) have identified hundreds of genetic variants
associated with autoimmune diseases and provided unique mechanistic insights and informed …
associated with autoimmune diseases and provided unique mechanistic insights and informed …
[HTML][HTML] Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus
Systemic lupus erythematosus is a heritable autoimmune disease that predominantly affects
young women. To improve our understanding of genetic etiology, we conduct multi-ancestry …
young women. To improve our understanding of genetic etiology, we conduct multi-ancestry …
[HTML][HTML] Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies
…, G Shenoy, O Marx, L Carrel, B Jiang… - Nature …, 2022 - nature.com
Transcriptome-wide association studies (TWAS) are popular approaches to test for association
between imputed gene expression levels and traits of interest. Here, we propose an …
between imputed gene expression levels and traits of interest. Here, we propose an …
[HTML][HTML] Model-based assessment of replicability for genome-wide association meta-analysis
Genome-wide association meta-analysis (GWAMA) is an effective approach to enlarge
sample sizes and empower the discovery of novel associations between genotype and …
sample sizes and empower the discovery of novel associations between genotype and …
Methods for the analysis and interpretation for rare variants associated with complex traits
With the advent of Next Generation Sequencing (NGS) technologies, whole genome and
whole exome DNA sequencing has become affordable for routine genetic studies. Coupled …
whole exome DNA sequencing has become affordable for routine genetic studies. Coupled …
A survey of group key management
B Jiang, X Hu - … conference on computer science and software …, 2008 - ieeexplore.ieee.org
Group-oriented applications are urgent in network communications for bandwidth economizations.
The security issues in multicast are also urgent to be addressed. And the group key …
The security issues in multicast are also urgent to be addressed. And the group key …
Association between subjective cognitive decline and social and emotional support in US adults
Subjective cognitive decline (SCD) has been linked to Alzheimer’s Disease in the literature.
However, little is known about whether SCD is associated with social/emotional support (…
However, little is known about whether SCD is associated with social/emotional support (…
[HTML][HTML] Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes
Meta-analysis of genetic association studies increases sample size and the power for
mapping complex traits. Existing methods are mostly developed for datasets without missing …
mapping complex traits. Existing methods are mostly developed for datasets without missing …