User profiles for Bidisha Sinha

Bidisha Sinha

Associate Professor, IISER Kolkata
Verified email at iiserkol.ac.in
Cited by 1887

[HTML][HTML] Cells respond to mechanical stress by rapid disassembly of caveolae

B Sinha, D Köster, R Ruez, P Gonnord, M Bastiani… - Cell, 2011 - cell.com
The functions of caveolae, the characteristic plasma membrane invaginations, remain debated.
Their abundance in cells experiencing mechanical stress led us to investigate their role …

[PDF][PDF] Cholesterol depletion by MβCD enhances cell membrane tension and its variations-reducing integrity

A Biswas, P Kashyap, S Datta, T Sengupta, B Sinha - Biophysical journal, 2019 - cell.com
Cholesterol depletion by methyl-β-cyclodextrin (MβCD) remodels the plasma membrane's
mechanics in cells and its interactions with the underlying cytoskeleton, whereas in red blood …

[PDF][PDF] Mapping cell membrane fluctuations reveals their active regulation and transient heterogeneities

A Biswas, A Alex, B Sinha - Biophysical journal, 2017 - cell.com
Shape fluctuations of the plasma membrane occur in all cells, are incessant, and are proposed
to affect membrane functioning. Although studies show how membrane fluctuations are …

[HTML][HTML] Cell spread area and traction forces determine myosin-II-based cortex thickness regulation

R Kumar, S Saha, B Sinha - … et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
Actomyosin network under the plasma membrane of cells forms a cortical layer that regulates
cellular deformations during different processes. What regulates the cortex? Characterized …

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

…, VV Gurchenkov, B Sinha… - Proceedings of the …, 2013 - National Acad Sciences
Deciphering the multifactorial determinants of tumor progression requires standardized high-throughput
preparation of 3D in vitro cellular assays. We present a simple microfluidic …

[HTML][HTML] Mechano-regulation by clathrin pit-formation and passive cholesterol-dependent tubules during de-adhesion

…, A Kundu, A Banerjee, D Mitra, B Sinha - Cellular and Molecular …, 2024 - Springer
Adherent cells ensure membrane homeostasis during de-adhesion by various mechanisms,
including endocytosis. Although mechano-chemical feedbacks involved in this process …

[HTML][HTML] Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells

M Dewulf, DV Köster, B Sinha… - Nature …, 2019 - nature.com
Caveolin-3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene
cause different types of myopathies with altered membrane integrity and repair, expression …

Smoke-free and tobacco-free colleges and universities in the United States

…, L Casey, C Hallett, C Douglas, B Sinha… - Tobacco …, 2020 - tobaccocontrol.bmj.com
Objective To describe the number and proportion of accredited, degree-granting institutions
with 100% smoke-free and 100% tobacco-free protections across the USA and by state. …

[HTML][HTML] Student tobacco use, secondhand smoke exposure, and policy beliefs before and after implementation of a tobacco-free campus policy: Analysis of five US …

…, S Jivani, A Jazwa, E Heath, PB Redmon, B Sinha… - Preventive …, 2022 - Elsevier
The adoption of comprehensive tobacco policies by colleges and universities may help
reduce student tobacco use. To this end, The American Cancer Society's Tobacco-Free …

Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

…, BP Sinha, J Sarif, R D'Rozario, DK Sinha, B Sinha… - Elife, 2024 - elifesciences.org
T cells are crucial for efficient antigen-specific immune responses and thus their migration
within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, …