Galaxy (homepage: https://galaxyproject.org , main public server: https://usegalaxy.org ) is a
web-based scientific analysis platform used by tens of thousands of scientists across the …

We present an update to our Galaxy-based web server for processing and visualizing
deeply sequenced data. Its core tool set, deepTools, allows users to perform complete …

We present a Galaxy based web server for processing and visualizing deeply sequenced
data. The web server's core functionality consists of a suite of newly developed tools, called …

High-throughput data production technologies, particularly ‘next-generation’ DNA sequencing,
have ushered in widespread and disruptive changes to biomedical research. Making …

The protein cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential negative regulator of
immune responses, and its loss causes fatal autoimmunity in mice. We studied a large family …

To the Editor: Bioinformatics software comes in a variety of programming languages and
requires diverse installation methods. This heterogeneity makes management of a software …

Despite an abundance of new studies about topologically associating domains (TADs), the
role of genetic information in TAD formation is still not fully understood. Here we use our …

Several lines of evidence indicate that prefibrillar assemblies of amyloid-β (Aβ) polypeptides,
such as soluble oligomers or protofibrils, rather than mature, end-stage amyloid fibrils …

Motivation Generating publication ready plots to display multiple genomic tracks can pose a
serious challenge. Making desirable and accurate figures requires considerable effort. This …

The heart is a highly specialized organ with essential function for the organism throughout
life. The significance of DNA methylation in shaping the phenotype of the heart remains only …